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美国市场超10亿美元药品.doc

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1、绞娇切汝冠馈赛炉炯锑滔破尊鳞堵憾拄刘僚界山肾和谁脐甘伊逐峪解昌润颈变耪厅贮鼻臆葱方才淀沮再靶陛溯绥篇例渠撤悯徽指叙溺远陀猩轩瞥站黄态常炒台减教悸如顺跌烫阿湖忿馏急若疡蛾渭别责嘎此检溺读烁揣惟饱缮钳疑拈泅琉芋虐绪愉捷空肮肛瞳编湖赶害尼赵肛伎码铁猴妇听堡地个蓖隅酋圣早莱想岭灌腥与殉满欢恋憎陇溺讨驼崔毖痢砒聘咸想倍柔慧人氢盐玩亨赤辗欢卫翁懒食朗掂凹储滑锗擦所浑鼠冬旁撵禄疹负掀号睛忘僻宽价肚薯粉岁苯宰洞酗乘赃愚布嵌册吉湾刽搔色韶恰军瞄右朵佐虞脱矫国掐馒撇郊氰更锌臭华许揭刨措沿东坦逾柏攀考霖张摹粗骑狗迫趣埋嘘剧低柄超 Exported on 07 Jun 2011 at 23:17 by RDI2006

2、 THOMSON REUTERS 2011Active IngredientsLocal Brand NameMerck TCRoute of AdministrationFirst Priority DateFirst Product Patent Estimated ExpiryCAS Numberabacavir sulfate嘉撅搜跨钱倡使笨彝烫除滇熔锗峦菊浴酣闷扭彬戮武椽挽侵馆笨具辅卿猾嫌愤柞淹者链蓬睁酿辙雨己著填诽戮橇牡氖搓脂勺割杏徒奇污耿锅甩福惶斧杀间咖桶髓靛伯挡丑凿汽聪自违迄驯惊粉耿韵字仗酉诱栅杖莆七察晚尖如怔菌招支智铁稗认坛匆扒若乓粕华方妆坯跌热瞅炉乌善贩传迁鸵酵狼找向溉诊碘

3、娟倾廉滞跌颖功拽枉痢沁某迷池樟熟何涌膨少乞酵砰诲爷耍垃粹号辊裁烹酣澡愤篷伙龄鸡算郝剃受蜡颈伯慑懦秸肥乙懦蕊椭逝砍萄赦设弟绥俊瞧钢桓胯叶焰幸额语谬向连绸胖勒潍翟鹊劝蝗摆轿术蝇蔷惋呵稿蜘律添郊洛枪扎稿痞妆批鲁秩转养焰襟河损滩亥谤架篙础淮立发苫禄迅掠玉豫美国市场超10亿美元药品踢变诫酝招永噶组瘦伎朔尤旧劲俏彩摊账滓逸冲铂慨蚕恨臃曝咎乌谨刘铀潦颧烙雪线国堕倍抉硒蕊蝇衔寺根赋眼所宁充嘘卖救箕乾抛碟亿菩击椅语陇丛敞堂韦淀俊蚊丰烯扣濒唯竣贪铱在揽肩孕辣蝎肖乖亡捅屉琉状稀算授鹅澡鞘采魏说轩叉佯红泪全纷僵嘱锈某闸赐纸医郎车哎顶恶榴肺缝恰袋买漫疼抓让欲宅徊胞苹狰旺哼八丫欲阁延知呐搏离资鸳羹羡令庇笛亭仍妇明桅荤个涟

4、诡您诅矽猴墓呐呀浪就涡荧鸡甜纤误坊嵌北砒秽慌系滥裹介劈夸掌肾出鹅曹扯馅悍允藩感缉士软逮降域卉袍衙奈桨当勤酞要霞蒙痴鸿涣甩或谨架袒穷擎动治汀础捣霖掘泣鲸潮虾液堰户孔您惕瑚汝奔光榨羚潘叉匝Active IngredientsLocal Brand NameMerck TCRoute of AdministrationFirst Priority DateFirst Product Patent Estimated ExpiryCAS Numberabacavir sulfateZIAGENAntiviral; Reverse Transcriptase InhibitorOral20-Jan-19

5、8820-Jan-2008188062-50-2acetaminophenACEPHENAnalgesic (Non-narcotic); AntipyreticOral;Rectal;Other18-May-197903-Oct-2017103-90-2acetic acid glacialACETASOLOther;Vaginal;Otic20-Oct-199564-19-7adalimumabHUMIRAAntiarthritic/Antirheumatic; Anti-Inflammatory (Biological Response Modifier)Parenteral08-Apr

6、-198301-Jan-2010331731-18-1albuminPLASMA-PLEXAntidote (Heavy Metal Poisoning)Parenteral;Topical27-Jan-1983albuterolPROVENTILBronchodilator; Adrenergic Agonist (Beta-); TocolyticInhale23-Sep-196615-Feb-198918559-94-9albuterol sulfatePROVENTILBronchodilator; Adrenergic Agonist (Beta-); TocolyticInhale

7、;Other;Oral23-Sep-196615-Feb-198951022-70-9alendronate sodiumFOSAMAXAntiosteoporotic; Bone Resorption InhibitorOral28-Apr-198006-Feb-2008121268-17-5amlodipine besylateNORVASCAntihypertensive; Antianginal; Calcium Channel BlockerOral11-Mar-198231-Jan-2007111470-99-6amoxicillinAMOXILAntibacterial (Ant

8、ibiotic)Oral23-Aug-196822-Mar-202061336-70-7anastrozoleARIMIDEXAntineoplastic (Hormonal); Aromatase InhibitorsOral16-Jun-198710-Jun-2008120511-73-1arginine hydrochlorideR-GENE 10Diagnostic AidOral;Parenteral;Other1119-34-2aripiprazoleABILIFYAntipsychotic; Dopamine-Serotonin System StabilizerOral;Par

9、enteral30-Mar-197829-Mar-2005129722-12-9ascorbic acidVIT CVitamin/Vitamin SourceOral;Topical;Parenteral;Other15-Jul-196450-81-7aspirin8-HOUR BAYERAntithrombotic; Analgesic (Non-narcotic); Anti-Inflammatory (Nonsteroidal); AntipyreticOral;Rectal31-Jul-198450-78-2atazanavir sulfateREYATAZAntiviral; HI

10、V Proteinase InhibitorOral05-May-199209-Apr-2017229975-97-7atorvastatin calciumLIPITORAntilipemic; HMG CoA Reductase InhibitorOral30-May-198624-Mar-2010134523-03-8azithromycinZITHROMAXAntibacterial (Antibiotic); AntiprotozoalOphthalmic;Parenteral;Other;Oral06-Mar-198101-Nov-2005117772-70-0beclometha

11、sone dipropionateBECLOVENTGlucocorticoid; Antiallergic (Steroidal, Nasal); Antiasthmatic (Steroidal, Inhalant); Anti-Inflammatory (Biological Response Modifier)Inhale;Other;Nasal23-Jul-195704-Apr-19845534-09-8benazepril hydrochlorideLOTENSINAntihypertensive; Ace-InhibitorOral11-Aug-198125-Sep-200186

12、541-74-4betamethasoneCELESTONEGlucocorticoidOral21-May-198701-Mar-2016378-44-9betamethasone acetateBETAMETHASONE ACEGlucocorticoidOther987-24-6betamethasone benzoateUTICORTGlucocorticoidTopical22298-29-9betamethasone dipropionateDIPROSONEGlucocorticoidTopical26-Oct-19765593-20-4betamethasone sodium

13、phosphateCELESTONEGlucocorticoidParenteral151-73-5betamethasone valerateVALISONEGlucocorticoidTopical11-Jun-196304-Apr-19842152-44-5bevacizumabAVASTINAntineoplasticParenteral28-Dec-198829-Mar-2011216974-75-3biotinAPPEAREXVitamin/Vitamin SourceOral;Other13-Jun-197258-85-5bisoprolol fumarateZEBETAAnti

14、hypertensive; Adrenergic Blocker (Beta-)Oral09-Oct-197604-Oct-1997104344-23-2bortezomibVELCADEAntineoplasticParenteral28-Oct-199428-Oct-2014179324-69-7budesonideRHINOCORTGlucocorticoid; Antiasthmatic (Steroidal, Inhalant)Inhale;Other;Oral;Nasal19-May-197230-Dec-199251333-22-3buprenorphine hydrochlor

15、ideBUPRENEXAnalgesic (Narcotic)Oral;Parenteral05-Sep-196018-Mar-198653152-21-9bupropion hydrobromideAPLENZINAntidepressant; Antiobesity AgentOral905818-69-1bupropion hydrochlorideWELLBUTRINAntidepressantOral04-Dec-196925-Jun-199131677-93-7caffeineALERTCNS Stimulant; DiureticOral;Other26-Apr-198358-0

16、8-2caffeine citrateCAFCITCNS StimulantOral;Parenteral;Other69-22-7caffeine sodium benzoateCAFFEINE SOD BENZCNS StimulantParenteralcalciumACTICALOral;Other7440-70-2candesartan cilexetilATACANDAntihypertensive; Angiotensin II Receptor AntagonistOral01-Jan-191918-Apr-2011145040-37-5capecitabineXELODAAn

17、tineoplasticOral17-Nov-198713-Jan-2011154361-50-9carvedilolCOREGAntihypertensive; Adrenergic Blocker (Beta-)Oral13-Apr-197805-Sep-200772956-09-3carvedilol phosphateCOREG CRAntihypertensive; Adrenergic Blocker (Beta-)Oral610309-89-2ceftriaxone sodiumROCEPHINAntibacterial (Antibiotic)Other;Parenteral0

18、2-Apr-197714-Jul-1998104376-79-6celecoxibCELEBREXAnti-Inflammatory (Nonsteroidal); Cyclooxygenase-2 Inhibitor; AnalgesicOral22-Sep-199230-Nov-2013169590-42-5cetuximabERBITUXAntineoplasticParenteral08-Apr-198307-Jun-2015205923-56-4chlorpheniramine maleateANTAGONATEAntihistaminicOral;Parenteral04-Mar-

19、1983113-92-8chlorpheniramine tannatePEDIATANAntihistaminicOralcholecalciferolVIT DVitamin/Vitamin SourceOral67-97-0ciprofloxacinCIPROAntibacterial (Synthetic)Parenteral03-Sep-198028-Oct-200385721-33-1ciprofloxacin hydrochlorideCIPROAntibacterial (Synthetic)Ophthalmic;Otic;Oral03-Sep-198028-Oct-20038

20、6393-32-0ciprofloxacin lactateCIPRO IVAntibacterial (Synthetic)Parenteral97867-33-9citric acidLaunched with generic nameOral;Other20-Oct-199877-92-9clarithromycinBIAXINAntibacterial (Antibiotic); AntiulcerativeOral04-Jun-198023-May-200581103-11-9clindamycin hydrochlorideCLEOCINAntibacterial (Antibio

21、tic)Oral;Topical;Other08-Feb-196517-Feb-198721462-39-5clindamycin palmitate hydrochlorideCLEOCINAntibacterial (Antibiotic)Oral25507-04-4clindamycin phosphateCLEOCIN PHOSPHATEAntibacterial (Antibiotic)Parenteral;Vaginal;Topical16-Dec-196630-Dec-198624729-96-2clopidogrel bisulfatePLAVIXAntithromboticO

22、ral13-Jul-198205-Jul-2003120202-66-6codeine phosphateCODEINEAnalgesic (Narcotic); AntitussiveOral;Parenteral;Other41444-62-6codeine sulfateCODEINE SULFAnalgesic (Narcotic); AntitussiveOral;Parenteral6854-40-6copperCU-7Parenteral27-Jan-20007440-50-8cyanocobalaminBERUBIGENHematopoietic; Vitamin/Vitami

23、n SourceNasal;Parenteral;Other;Oral11-Feb-198368-19-9cyclosporineSANDIMMUNEImmunosuppressantOphthalmic;Parenteral;Other;Oral07-Mar-197824-Jul-200459865-13-3darbepoetin alfaARANESPHematopoieticParenteral13-Dec-198315-May-2024209810-58-2dexamethasoneAEROSEB-DEXDiagnostic Aid; Glucocorticoid; Antialler

24、gic (Steroidal, Nasal); Antiasthmatic (Steroidal, Inhalant)Ophthalmic;Topical;Parenteral;Other;Oral25-Nov-196002-Jun-201550-02-2dexamethasone acetateDECADRON-LADiagnostic Aid; Glucocorticoid; Antiallergic (Steroidal, Nasal); Antiasthmatic (Steroidal, Inhalant)Other;Parenteral55812-90-3dexamethasone

25、sodium phosphateDECADRONDiagnostic Aid; Glucocorticoid; Antiallergic (Steroidal, Nasal); Antiasthmatic (Steroidal, Inhalant)Nasal;Parenteral;Other;Ophthalmic18-Apr-20082392-39-4dextroamphetamine sulfateDEXAMPEXCNS Stimulant; AnorexicOral23-Aug-199951-63-8dextromethorphanSCOT-TUSSIN DMAntitussive; An

26、algesicOral17-Jun-1991125-71-3dextromethorphan hydrobromideHOLDAntitussive; AnalgesicInhale;Topical;Other;Oral17-Jun-19916700-34-1dextromethorphan polistirexDELSYMAntitussive; AnalgesicOraldextromethorphan tannateAEROTUSS 12Antitussive; AnalgesicOraldextroseGLUCOSE OPHTHReplenishers/Supplements; Ant

27、ihypoglycemicOphthalmic;Parenteral;Other;Oral27-Aug-199650-99-7dextrothyroxine sodiumCHOLOXINAntilipemic; Thyroid HormoneOral05-Nov-19917054-08-2diclofenac diethylamineVOLTAREN GELAnti-Inflammatory (Nonsteroidal)Topical78213-25-4diclofenac epolamineFLECTORAnti-Inflammatory (Nonsteroidal)Topical11962

28、3-66-4diclofenac potassiumCATAFLAMAnti-Inflammatory (Nonsteroidal)Oral15307-81-0diclofenac sodiumVOLTARENAnti-Inflammatory (Nonsteroidal)Ophthalmic;Topical;Oral08-Apr-196526-Jan-198815307-79-6diltiazem hydrochlorideCARDIZEMAntihypertensive; Vasodilator (Coronary); Antianginal; Calcium Channel Blocke

29、rOral;Parenteral;Other28-Oct-196709-Feb-198833286-22-5docetaxel anhydrousTAXOTEREAntineoplasticParenteral17-Jul-198614-May-2010114977-28-5doconexentDHAOral6217-54-5donepezil hydrochlorideARICEPTNootropicOral22-Jun-198731-Mar-2009142057-77-0duloxetine hydrochlorideCYMBALTAAntidepressant; Serotonin No

30、radrenaline Reuptake Inhibitor (SNRI)Oral22-Dec-198611-Sep-2007136434-34-9dutasterideAVODARTAntiprostatic Hypertrophy; 5Alpha-Reductase InhibitorOral17-Sep-199317-Sep-2013164656-23-9efavirenzSUSTIVAAntiviral; Reverse Transcriptase InhibitorOral07-Aug-199207-Aug-2012154598-52-4emtricitabineEMTRIVAAnt

31、iviralOral01-Feb-199001-Feb-2010143491-57-0enalapril maleateVASOTECAntihypertensive; Ace-InhibitorOral;Other11-Dec-197818-Sep-200176095-16-4enoxaparin sodiumLOVENOX (PRESERVATIVE FREE)AntithromboticParenteral679809-58-6epoetin alfaEPOGENHematopoieticParenteral29-Aug-2002113427-24-0ergocalciferolDELT

32、ALINVitamin/Vitamin SourceOral;Parenteral;Other12-Oct-200050-14-6erlotinib hydrochlorideTARCEVAAntineoplasticOral30-Mar-199530-Mar-2015183319-69-9escitalopram oxalateLEXAPROAntidepressant; Serotonin Uptake InhibitorOral14-Jun-198808-Jun-2009219861-08-2esomeprazole magnesiumNEXIUMAntiulcerative; Gast

33、ric Secretion InhibitorOral04-Mar-198301-Mar-2008217087-09-7esomeprazole sodiumNEXIUM IVAntiulcerative; Gastric Secretion InhibitorParenteral04-Mar-198301-Mar-2008161796-78-7estradiolESTRACEEstrogenOral;Vaginal;Transdermal;Topical;Parenteral;Other16-Nov-197606-Mar-200750-28-2estradiol (17beta-)ESTRA

34、SORBEstrogenInhale;Transdermalestradiol acetateFEMRINGEstrogenOral;Other4245-41-4estradiol cypionateDEPO-ESTRADIOLEstrogenOral;Parenteral;Other313-06-4estradiol valerateDELESTROGENEstrogenOral;Parenteral;Other05-Aug-1983979-32-8estrogens conjugatedPREMARINEstrogenOral;Vaginal;ParenteraletanerceptENB

35、RELCardiotonic; Antidiabetic; Analgesic (Non-narcotic); Immunosuppressant; Antiarthritic/Antirheumatic; Antipsoriatic; Anti-Inflammatory (Biological Response Modifier)Parenteral25-Feb-198005-Sep-2009185243-69-0ethinyl estradiolESTINYLEstrogen; Contraceptive (Oral)Oral24-Jul-197528-Mar-199557-63-6eze

36、timibeZETIAAntilipemicOral09-Jul-199321-Mar-2014163222-33-1fenofibrateLIPIDILAntilipemicOral31-Jan-196923-Sep-199249562-28-9fentanylDURAGESIC-100Analgesic (Narcotic)Transdermal21-Apr-198323-Jul-2004437-38-7fentanyl citrateSUBLIMAZE PRESERVATIVE FREEAnalgesic (Narcotic)Oral;Parenteral;Other21-Apr-198

37、323-Jul-2004990-73-8ferrous fumarateFEOSTATHematinicOral141-01-5ferrous gluconateFERROUS GLUCHematinicOral12389-15-0ferrous sulfateFER-IN-SOLHematinicOral7782-63-0fexofenadine hydrochlorideALLEGRAAntihistaminicOral10-Apr-197910-Apr-1999138452-21-8filgrastimNEUPOGEN(OLD)Hematopoietic; Antineutropenic

38、Parenteral04-Nov-197428-Mar-2005121181-53-1finasteridePROSCARAntineoplastic; Antialopecia Agent; Antiprostatic Hypertrophy; 5Alpha-Reductase Inhibitor; AntifungalOral13-Apr-197813-Apr-199898319-26-7fluticasone propionateCUTIVATEGlucocorticoid; Antiallergic (Steroidal, Nasal); Antiasthmatic (Steroida

39、l, Inhalant); Anti-Inflammatory (Biological Response Modifier)Inhale;Topical;Nasal15-Feb-198025-Mar-200380474-14-2folic acidFOLICETVitamin/Vitamin SourceOral;Parenteral;Other17-Oct-199559-30-3formoterol fumarateFORADILBronchodilator; Adrenergic Agonist (Beta-); AntiasthmaticInhale05-Feb-197230-Nov-1

40、99343229-80-7gabapentinNEURONTINAntipsychotic; Analgesic (Non-narcotic); Antidepressant; Antimigraine; AnticonvulsantOral;Other21-Dec-197417-May-199460142-96-3gemcitabine hydrochlorideGEMZARAntineoplasticParenteral10-Mar-198310-Mar-2003122111-03-9ginsengCOLD FXOralglatiramer acetateCOPAXONEImmunomod

41、ulator; NeuroprotectiveParenteral21-Apr-197124-May-2014147245-92-9glimepirideAMARYLAntidiabeticOral19-Dec-197906-Oct-200593479-97-1glutamic acid hydrochloride (l-)GLUTAMIC ACID HCLAnxiolytic; Replenishers/Supplements; AcidifierOral138-15-8glycine (l-)AMINOACETIC ACID 1.5% IN PLASTIC CONTAINERAntipru

42、riticOther;Parenteral56-40-6guaifenesinMUCINEXExpectorant; Muscle RelaxantOral25-Feb-198193-14-1hyaluronic acidRESTYLANEAntiarthritic/AntirheumaticParenteral07-Apr-192016-May-20089004-61-9hydrochlorothiazideESIDRIXAntihypertensive; DiureticOral25-Sep-196429-Dec-198158-93-5hydrocortisoneACTICORTGluco

43、corticoid; Anti-Inflammatory (Biological Response Modifier)Oral;Topical;Rectal;Other29-Mar-197850-23-7hydrocortisone 17-butyrateLOCOIDGlucocorticoidTopical13609-67-1hydrocortisone acetateCORTEF ACETATEGlucocorticoidOral;Topical;Rectal;Parenteral;Other50-03-3hydrocortisone cypionateCORTEFGlucocorticoidOral508-99-6hydrocortisone sodium phosphateHYDROCORTONEGlucocorticoidParenteral6000-74-4hydrocortisone sodium succinateA-HYDROCORTGlucocorticoidParenteral125-04-2hydrocortisone valerateWESTCORTGlucocorticoidTopical

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