美国市场超10亿美元药品.doc

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Exported on 07 Jun 2011 at 23:17 by RDI2006
© THOMSON REUTERS 2011

Active Ingredients
Local Brand Name
Merck TC
Route of Administration
First Priority Date
First Product Patent Estimated Expiry
CAS Number
abacavir sulfate
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Active Ingredients
Local Brand Name
Merck TC
Route of Administration
First Priority Date
First Product Patent Estimated Expiry
CAS Number
abacavir sulfate
ZIAGEN
Antiviral; Reverse Transcriptase Inhibitor
Oral
20-Jan-1988
20-Jan-2008
188062-50-2
acetaminophen
ACEPHEN
Analgesic (Non-narcotic); Antipyretic
Oral;Rectal;Other
18-May-1979
03-Oct-2017
103-90-2
acetic acid glacial
ACETASOL

Other;Vaginal;Otic
20-Oct-1995

64-19-7
adalimumab
HUMIRA
Antiarthritic/Antirheumatic; Anti-Inflammatory (Biological Response Modifier)
Parenteral
08-Apr-1983
01-Jan-2010
331731-18-1
albumin
PLASMA-PLEX
Antidote (Heavy Metal Poisoning)
Parenteral;Topical
27-Jan-1983

albuterol
PROVENTIL
Bronchodilator; Adrenergic Agonist (Beta-); Tocolytic
Inhale
23-Sep-1966
15-Feb-1989
18559-94-9
albuterol sulfate
PROVENTIL
Bronchodilator; Adrenergic Agonist (Beta-); Tocolytic
Inhale;Other;Oral
23-Sep-1966
15-Feb-1989
51022-70-9
alendronate sodium
FOSAMAX
Antiosteoporotic; Bone Resorption Inhibitor
Oral
28-Apr-1980
06-Feb-2008
121268-17-5
amlodipine besylate
NORVASC
Antihypertensive; Antianginal; Calcium Channel Blocker
Oral
11-Mar-1982
31-Jan-2007
111470-99-6
amoxicillin
AMOXIL
Antibacterial (Antibiotic)
Oral
23-Aug-1968
22-Mar-2020
61336-70-7
anastrozole
ARIMIDEX
Antineoplastic (Hormonal); Aromatase Inhibitors
Oral
16-Jun-1987
10-Jun-2008
120511-73-1
arginine hydrochloride
R-GENE 10
Diagnostic Aid
Oral;Parenteral;Other

1119-34-2
aripiprazole
ABILIFY
Antipsychotic; Dopamine-Serotonin System Stabilizer
Oral;Parenteral
30-Mar-1978
29-Mar-2005
129722-12-9
ascorbic acid
VIT C
Vitamin/Vitamin Source
Oral;Topical;Parenteral;Other
15-Jul-1964

50-81-7
aspirin
8-HOUR BAYER
Antithrombotic; Analgesic (Non-narcotic); Anti-Inflammatory (Nonsteroidal); Antipyretic
Oral;Rectal
31-Jul-1984

50-78-2
atazanavir sulfate
REYATAZ
Antiviral; HIV Proteinase Inhibitor
Oral
05-May-1992
09-Apr-2017
229975-97-7
atorvastatin calcium
LIPITOR
Antilipemic; HMG CoA Reductase Inhibitor
Oral
30-May-1986
24-Mar-2010
134523-03-8
azithromycin
ZITHROMAX
Antibacterial (Antibiotic); Antiprotozoal
Ophthalmic;Parenteral;Other;Oral
06-Mar-1981
01-Nov-2005
117772-70-0
beclomethasone dipropionate
BECLOVENT
Glucocorticoid; Antiallergic (Steroidal, Nasal); Antiasthmatic (Steroidal, Inhalant); Anti-Inflammatory (Biological Response Modifier)
Inhale;Other;Nasal
23-Jul-1957
04-Apr-1984
5534-09-8
benazepril hydrochloride
LOTENSIN
Antihypertensive; Ace-Inhibitor
Oral
11-Aug-1981
25-Sep-2001
86541-74-4
betamethasone
CELESTONE
Glucocorticoid
Oral
21-May-1987
01-Mar-2016
378-44-9
betamethasone acetate
BETAMETHASONE ACE
Glucocorticoid
Other

987-24-6
betamethasone benzoate
UTICORT
Glucocorticoid
Topical

22298-29-9
betamethasone dipropionate
DIPROSONE
Glucocorticoid
Topical
26-Oct-1976

5593-20-4
betamethasone sodium phosphate
CELESTONE
Glucocorticoid
Parenteral

151-73-5
betamethasone valerate
VALISONE
Glucocorticoid
Topical
11-Jun-1963
04-Apr-1984
2152-44-5
bevacizumab
AVASTIN
Antineoplastic
Parenteral
28-Dec-1988
29-Mar-2011
216974-75-3
biotin
APPEAREX
Vitamin/Vitamin Source
Oral;Other
13-Jun-1972

58-85-5
bisoprolol fumarate
ZEBETA
Antihypertensive; Adrenergic Blocker (Beta-)
Oral
09-Oct-1976
04-Oct-1997
104344-23-2
bortezomib
VELCADE
Antineoplastic
Parenteral
28-Oct-1994
28-Oct-2014
179324-69-7
budesonide
RHINOCORT
Glucocorticoid; Antiasthmatic (Steroidal, Inhalant)
Inhale;Other;Oral;Nasal
19-May-1972
30-Dec-1992
51333-22-3
buprenorphine hydrochloride
BUPRENEX
Analgesic (Narcotic)
Oral;Parenteral
05-Sep-1960
18-Mar-1986
53152-21-9
bupropion hydrobromide
APLENZIN
Antidepressant; Antiobesity Agent
Oral

905818-69-1
bupropion hydrochloride
WELLBUTRIN
Antidepressant
Oral
04-Dec-1969
25-Jun-1991
31677-93-7
caffeine
ALERT
CNS Stimulant; Diuretic
Oral;Other
26-Apr-1983

58-08-2
caffeine citrate
CAFCIT
CNS Stimulant
Oral;Parenteral;Other

69-22-7
caffeine sodium benzoate
CAFFEINE SOD BENZ
CNS Stimulant
Parenteral

calcium
ACTICAL

Oral;Other

7440-70-2
candesartan cilexetil
ATACAND
Antihypertensive; Angiotensin II Receptor Antagonist
Oral
01-Jan-1919
18-Apr-2011
145040-37-5
capecitabine
XELODA
Antineoplastic
Oral
17-Nov-1987
13-Jan-2011
154361-50-9
carvedilol
COREG
Antihypertensive; Adrenergic Blocker (Beta-)
Oral
13-Apr-1978
05-Sep-2007
72956-09-3
carvedilol phosphate
COREG CR
Antihypertensive; Adrenergic Blocker (Beta-)
Oral

610309-89-2
ceftriaxone sodium
ROCEPHIN
Antibacterial (Antibiotic)
Other;Parenteral
02-Apr-1977
14-Jul-1998
104376-79-6
celecoxib
CELEBREX
Anti-Inflammatory (Nonsteroidal); Cyclooxygenase-2 Inhibitor; Analgesic
Oral
22-Sep-1992
30-Nov-2013
169590-42-5
cetuximab
ERBITUX
Antineoplastic
Parenteral
08-Apr-1983
07-Jun-2015
205923-56-4
chlorpheniramine maleate
ANTAGONATE
Antihistaminic
Oral;Parenteral
04-Mar-1983

113-92-8
chlorpheniramine tannate
PEDIATAN
Antihistaminic
Oral

cholecalciferol
VIT D
Vitamin/Vitamin Source
Oral

67-97-0
ciprofloxacin
CIPRO
Antibacterial (Synthetic)
Parenteral
03-Sep-1980
28-Oct-2003
85721-33-1
ciprofloxacin hydrochloride
CIPRO
Antibacterial (Synthetic)
Ophthalmic;Otic;Oral
03-Sep-1980
28-Oct-2003
86393-32-0
ciprofloxacin lactate
CIPRO IV
Antibacterial (Synthetic)
Parenteral

97867-33-9
citric acid
Launched with generic name

Oral;Other
20-Oct-1998

77-92-9
clarithromycin
BIAXIN
Antibacterial (Antibiotic); Antiulcerative
Oral
04-Jun-1980
23-May-2005
81103-11-9
clindamycin hydrochloride
CLEOCIN
Antibacterial (Antibiotic)
Oral;Topical;Other
08-Feb-1965
17-Feb-1987
21462-39-5
clindamycin palmitate hydrochloride
CLEOCIN
Antibacterial (Antibiotic)
Oral

25507-04-4
clindamycin phosphate
CLEOCIN PHOSPHATE
Antibacterial (Antibiotic)
Parenteral;Vaginal;Topical
16-Dec-1966
30-Dec-1986
24729-96-2
clopidogrel bisulfate
PLAVIX
Antithrombotic
Oral
13-Jul-1982
05-Jul-2003
120202-66-6
codeine phosphate
CODEINE
Analgesic (Narcotic); Antitussive
Oral;Parenteral;Other

41444-62-6
codeine sulfate
CODEINE SULF
Analgesic (Narcotic); Antitussive
Oral;Parenteral

6854-40-6
copper
CU-7

Parenteral
27-Jan-2000

7440-50-8
cyanocobalamin
BERUBIGEN
Hematopoietic; Vitamin/Vitamin Source
Nasal;Parenteral;Other;Oral
11-Feb-1983

68-19-9
cyclosporine
SANDIMMUNE
Immunosuppressant
Ophthalmic;Parenteral;Other;Oral
07-Mar-1978
24-Jul-2004
59865-13-3
darbepoetin alfa
ARANESP
Hematopoietic
Parenteral
13-Dec-1983
15-May-2024
209810-58-2
dexamethasone
AEROSEB-DEX
Diagnostic Aid; Glucocorticoid; Antiallergic (Steroidal, Nasal); Antiasthmatic (Steroidal, Inhalant)
Ophthalmic;Topical;Parenteral;Other;Oral
25-Nov-1960
02-Jun-2015
50-02-2
dexamethasone acetate
DECADRON-LA
Diagnostic Aid; Glucocorticoid; Antiallergic (Steroidal, Nasal); Antiasthmatic (Steroidal, Inhalant)
Other;Parenteral

55812-90-3
dexamethasone sodium phosphate
DECADRON
Diagnostic Aid; Glucocorticoid; Antiallergic (Steroidal, Nasal); Antiasthmatic (Steroidal, Inhalant)
Nasal;Parenteral;Other;Ophthalmic
18-Apr-2008

2392-39-4
dextroamphetamine sulfate
DEXAMPEX
CNS Stimulant; Anorexic
Oral
23-Aug-1999

51-63-8
dextromethorphan
SCOT-TUSSIN DM
Antitussive; Analgesic
Oral
17-Jun-1991

125-71-3
dextromethorphan hydrobromide
HOLD
Antitussive; Analgesic
Inhale;Topical;Other;Oral
17-Jun-1991

6700-34-1
dextromethorphan polistirex
DELSYM
Antitussive; Analgesic
Oral

dextromethorphan tannate
AEROTUSS 12
Antitussive; Analgesic
Oral

dextrose
GLUCOSE OPHTH
Replenishers/Supplements; Antihypoglycemic
Ophthalmic;Parenteral;Other;Oral
27-Aug-1996

50-99-7
dextrothyroxine sodium
CHOLOXIN
Antilipemic; Thyroid Hormone
Oral
05-Nov-1991

7054-08-2
diclofenac diethylamine
VOLTAREN GEL
Anti-Inflammatory (Nonsteroidal)
Topical

78213-25-4
diclofenac epolamine
FLECTOR
Anti-Inflammatory (Nonsteroidal)
Topical

119623-66-4
diclofenac potassium
CATAFLAM
Anti-Inflammatory (Nonsteroidal)
Oral

15307-81-0
diclofenac sodium
VOLTAREN
Anti-Inflammatory (Nonsteroidal)
Ophthalmic;Topical;Oral
08-Apr-1965
26-Jan-1988
15307-79-6
diltiazem hydrochloride
CARDIZEM
Antihypertensive; Vasodilator (Coronary); Antianginal; Calcium Channel Blocker
Oral;Parenteral;Other
28-Oct-1967
09-Feb-1988
33286-22-5
docetaxel anhydrous
TAXOTERE
Antineoplastic
Parenteral
17-Jul-1986
14-May-2010
114977-28-5
doconexent
DHA

Oral

6217-54-5
donepezil hydrochloride
ARICEPT
Nootropic
Oral
22-Jun-1987
31-Mar-2009
142057-77-0
duloxetine hydrochloride
CYMBALTA
Antidepressant; Serotonin Noradrenaline Reuptake Inhibitor (SNRI)
Oral
22-Dec-1986
11-Sep-2007
136434-34-9
dutasteride
AVODART
Antiprostatic Hypertrophy; 5Alpha-Reductase Inhibitor
Oral
17-Sep-1993
17-Sep-2013
164656-23-9
efavirenz
SUSTIVA
Antiviral; Reverse Transcriptase Inhibitor
Oral
07-Aug-1992
07-Aug-2012
154598-52-4
emtricitabine
EMTRIVA
Antiviral
Oral
01-Feb-1990
01-Feb-2010
143491-57-0
enalapril maleate
VASOTEC
Antihypertensive; Ace-Inhibitor
Oral;Other
11-Dec-1978
18-Sep-2001
76095-16-4
enoxaparin sodium
LOVENOX (PRESERVATIVE FREE)
Antithrombotic
Parenteral

679809-58-6
epoetin alfa
EPOGEN
Hematopoietic
Parenteral
29-Aug-2002

113427-24-0
ergocalciferol
DELTALIN
Vitamin/Vitamin Source
Oral;Parenteral;Other
12-Oct-2000

50-14-6
erlotinib hydrochloride
TARCEVA
Antineoplastic
Oral
30-Mar-1995
30-Mar-2015
183319-69-9
escitalopram oxalate
LEXAPRO
Antidepressant; Serotonin Uptake Inhibitor
Oral
14-Jun-1988
08-Jun-2009
219861-08-2
esomeprazole magnesium
NEXIUM
Antiulcerative; Gastric Secretion Inhibitor
Oral
04-Mar-1983
01-Mar-2008
217087-09-7
esomeprazole sodium
NEXIUM IV
Antiulcerative; Gastric Secretion Inhibitor
Parenteral
04-Mar-1983
01-Mar-2008
161796-78-7
estradiol
ESTRACE
Estrogen
Oral;Vaginal;Transdermal;Topical;Parenteral;Other
16-Nov-1976
06-Mar-2007
50-28-2
estradiol (17beta-)
ESTRASORB
Estrogen
Inhale;Transdermal

estradiol acetate
FEMRING
Estrogen
Oral;Other

4245-41-4
estradiol cypionate
DEPO-ESTRADIOL
Estrogen
Oral;Parenteral;Other

313-06-4
estradiol valerate
DELESTROGEN
Estrogen
Oral;Parenteral;Other
05-Aug-1983

979-32-8
estrogens conjugated
PREMARIN
Estrogen
Oral;Vaginal;Parenteral

etanercept
ENBREL
Cardiotonic; Antidiabetic; Analgesic (Non-narcotic); Immunosuppressant; Antiarthritic/Antirheumatic; Antipsoriatic; Anti-Inflammatory (Biological Response Modifier)
Parenteral
25-Feb-1980
05-Sep-2009
185243-69-0
ethinyl estradiol
ESTINYL
Estrogen; Contraceptive (Oral)
Oral
24-Jul-1975
28-Mar-1995
57-63-6
ezetimibe
ZETIA
Antilipemic
Oral
09-Jul-1993
21-Mar-2014
163222-33-1
fenofibrate
LIPIDIL
Antilipemic
Oral
31-Jan-1969
23-Sep-1992
49562-28-9
fentanyl
DURAGESIC-100
Analgesic (Narcotic)
Transdermal
21-Apr-1983
23-Jul-2004
437-38-7
fentanyl citrate
SUBLIMAZE PRESERVATIVE FREE
Analgesic (Narcotic)
Oral;Parenteral;Other
21-Apr-1983
23-Jul-2004
990-73-8
ferrous fumarate
FEOSTAT
Hematinic
Oral

141-01-5
ferrous gluconate
FERROUS GLUC
Hematinic
Oral

12389-15-0
ferrous sulfate
FER-IN-SOL
Hematinic
Oral

7782-63-0
fexofenadine hydrochloride
ALLEGRA
Antihistaminic
Oral
10-Apr-1979
10-Apr-1999
138452-21-8
filgrastim
NEUPOGEN(OLD)
Hematopoietic; Antineutropenic
Parenteral
04-Nov-1974
28-Mar-2005
121181-53-1
finasteride
PROSCAR
Antineoplastic; Antialopecia Agent; Antiprostatic Hypertrophy; 5Alpha-Reductase Inhibitor; Antifungal
Oral
13-Apr-1978
13-Apr-1998
98319-26-7
fluticasone propionate
CUTIVATE
Glucocorticoid; Antiallergic (Steroidal, Nasal); Antiasthmatic (Steroidal, Inhalant); Anti-Inflammatory (Biological Response Modifier)
Inhale;Topical;Nasal
15-Feb-1980
25-Mar-2003
80474-14-2
folic acid
FOLICET
Vitamin/Vitamin Source
Oral;Parenteral;Other
17-Oct-1995

59-30-3
formoterol fumarate
FORADIL
Bronchodilator; Adrenergic Agonist (Beta-); Antiasthmatic
Inhale
05-Feb-1972
30-Nov-1993
43229-80-7
gabapentin
NEURONTIN
Antipsychotic; Analgesic (Non-narcotic); Antidepressant; Antimigraine; Anticonvulsant
Oral;Other
21-Dec-1974
17-May-1994
60142-96-3
gemcitabine hydrochloride
GEMZAR
Antineoplastic
Parenteral
10-Mar-1983
10-Mar-2003
122111-03-9
ginseng
COLD FX

Oral

glatiramer acetate
COPAXONE
Immunomodulator; Neuroprotective
Parenteral
21-Apr-1971
24-May-2014
147245-92-9
glimepiride
AMARYL
Antidiabetic
Oral
19-Dec-1979
06-Oct-2005
93479-97-1
glutamic acid hydrochloride (l-)
GLUTAMIC ACID HCL
Anxiolytic; Replenishers/Supplements; Acidifier
Oral

138-15-8
glycine (l-)
AMINOACETIC ACID 1.5% IN PLASTIC CONTAINER
Antipruritic
Other;Parenteral

56-40-6
guaifenesin
MUCINEX
Expectorant; Muscle Relaxant
Oral
25-Feb-1981

93-14-1
hyaluronic acid
RESTYLANE
Antiarthritic/Antirheumatic
Parenteral
07-Apr-1920
16-May-2008
9004-61-9
hydrochlorothiazide
ESIDRIX
Antihypertensive; Diuretic
Oral
25-Sep-1964
29-Dec-1981
58-93-5
hydrocortisone
ACTICORT
Glucocorticoid; Anti-Inflammatory (Biological Response Modifier)
Oral;Topical;Rectal;Other
29-Mar-1978

50-23-7
hydrocortisone 17-butyrate
LOCOID
Glucocorticoid
Topical

13609-67-1
hydrocortisone acetate
CORTEF ACETATE
Glucocorticoid
Oral;Topical;Rectal;Parenteral;Other

50-03-3
hydrocortisone cypionate
CORTEF
Glucocorticoid
Oral

508-99-6
hydrocortisone sodium phosphate
HYDROCORTONE
Glucocorticoid
Parenteral

6000-74-4
hydrocortisone sodium succinate
A-HYDROCORT
Glucocorticoid
Parenteral

125-04-2
hydrocortisone valerate
WESTCORT
Glucocorticoid
Topical