1、中中枢枢神神经经系系统统影影像像诊诊断断协协和和医医院院放放射射科科孔孔祥祥泉泉一、Examinationmethods1.X-rayplainfilmThismethodisverysimpleandcheap.Somelesionscanbefoundbyit.Usuallywecannotreachtoanexactdiagnosisonlybythisexamination2.Tomography2.TomographyExactdiagnosisstillcannotobtained ThemethodcanmanifestedsomeosseousThemethodcanmanif
2、estedsomeosseousdestructionwhichcannotbeshownbyplainfilm.destructionwhichcannotbeshownbyplainfilm.EnhancementEnhancement:3.CT Todisplaytumors,hemorrhage,infarction,infectionandabnormality.Todisplaytumors,hemorrhage,infarction,infectionandabnormality.ToshowtheabnormalToshowtheabnormalisodensityisoden
3、sitywhichcannotfoundbytheplainscan.whichcannotfoundbytheplainscan.Toconfirmthequalityofthelesion.Toconfirmthequalityofthelesion.Differentialdiagnosisoftumorandedema.Differentialdiagnosisoftumorandedema.PlainscanPlainscan:Thecharactersofthelesionincludingsize,appearance,number,Thecharactersofthelesio
4、nincludingsize,appearance,number,position,anatomyrelation,andsooncanbeshownbyit.position,anatomyrelation,andsooncanbeshownbyit.4.MagneticresonanceimagingPlainscanPlainscan:EnhancementEnhancement:ToshowtheabnormalToshowtheabnormalisodensityisodensitywhichcannotfoundbytheplainscan.whichcannotfoundbyth
5、eplainscan.Toconfirmthequalityofthelesion.Toconfirmthequalityofthelesion.Differentialdiagnosisoftumorandedema.Differentialdiagnosisoftumorandedema.MRA:Toshowthevascularlesionssuchasaneurysmandarterialvenousmalformation.Todisplaytumors,hemorrhage,infarction,infectionandabnormality.Todisplaytumors,hem
6、orrhage,infarction,infectionandabnormality.Thecharactersofthelesionincludingsize,appearance,number,Thecharactersofthelesionincludingsize,appearance,number,position,anatomyrelation,andsooncanbeshownbyit.position,anatomyrelation,andsooncanbeshownbyit.5.DSAToshowthevascularlesionssuchasaneurysm,arteria
7、lvenousmalformation.,bloodsupplyofneoplasm6.MyelographyToshowwhethertherearetumorsandobstructioninspinalcanal.Itisalsohelpfultoensurethepositionanddegreeofobstruction.一、一、Normalmanifestation(一)、(一)、(一)、(一)、PlainfilmPlainfilm1.Cranium1.Cranium TheinnerandouterplatearedenseandtheTheinnerandouterplatea
8、redenseandthediploediploeisspongy.isspongy.2.2.SkullsutureSkullsuture AllofthesuturesareshownasAllofthesuturesareshownassawtoothsawtoothshadowshadow3.Convolutionalimpressions Multipleroundlowdensityinplainfilm.Multipleroundlowdensityinplainfilm.4.Theimpressionofthemiddle4.Theimpressionofthemiddlemen
9、ingealmeningealarteryartery TheTheimpresstionimpresstionofthemiddleofthemiddlemeningealmeningealarteryispresentedasarteryispresentedasstreaksshadowandgooutfromwidetonarrowstreaksshadowandgooutfromwidetonarrow5.5.ImpressionImpressionofofd diploiciploicveinvein7.7.TheTheSellaSella:6.6.ImpressionofImpr
10、essionofpacchionianpacchioniangranulationgranulation8.Internalauditory8.Internalauditorymeatusmeatus:About6mmwide,symmetricalcanalAbout6mmwide,symmetricalcanalThefrontalparietalirregularThefrontalparietalirregularhypodensityhypodensitynearthemidline.nearthemidline.TheThediploicdiploicveinsimpressapp
11、earsasnetlikeveinsimpressappearsasnetlikehypodensityhypodensityintheintheparietalregion.parietalregion.716mmlong,714mmwideand820mmdeep.716mmlong,714mmwideand820mmdeep.10.calcificationof10.calcificationoffalxfalx cerebricerebri:9.9.CalcificationofCalcificationofpinealbody:pinealbody:11.Calcificationo
12、f11.Calcificationofchoroidchoroidplexusplexus12Calcificationof12Calcificationofpetro-clinoidpetro-clinoidligament:ligament:ItispresentedasnodularItispresentedasnodularhyperdensityhyperdensityonthelateralskullradiograph.onthelateralskullradiograph.ThefrontalviewshowthenormalpositionarepresentedtheThe
13、frontalviewshowthenormalpositionarepresentedthezonaryzonarydenseimageonthemidline.denseimageonthemidline.CalcificationofCalcificationofchoroidchoroidplexusarepresentedtheanomalisticdenseplexusarepresentedtheanomalisticdenseimageandlateraltomidline.imageandlateraltomidline.Thedenseshadowbetweeninthea
14、nteriorandposteriorThedenseshadowbetweenintheanteriorandposteriorclinoidclinoidprocess.process.1.1.WWhitematter:hitematter:isishypodensehypodensetograymatter.CTvaluesistograymatter.CTvaluesis20-30Hu20-30Hu2.Graymatter:2.Graymatter:isishyperdensehyperdensetowhitematter.CTvaluesistowhitematter.CTvalue
15、sis30-40Hu30-40Hu 3.Ventricleandcistern:3.Ventricleandcistern:arearehypodensehypodense.CTvaluesis.CTvaluesis0-10Hu0-10Hu 4.Skull:4.Skull:isishyperdensehyperdense.CTvalues.CTvalues250Hu250Hu5.Physiologicalcalcification:5.Physiologicalcalcification:Spotorpatchdenseshadow.CTvalues60Hu二、二、CTmanifestatio
16、n三、三、MRImanifestation1.MorphologicalmanifestationAxial,coronal,sagittalMRIcanclearlyshowtheshapeofbrainandspinalcord,suchaswhitematter,greymatter,ventricle,cerebralfissure,brainstem,cerebralvessel,pituitarybody,etal.Theefficiencyisclosetogrossspecimen.T1WIT2WIT1WIT2WIWHITEMATTERHIGHLOWWHITEMATTERHIG
17、HLOWGREYMATTERLOWHIGHGREYMATTERLOWHIGHCSFLOWHIGHCSFLOWHIGHFATHIGHMEDIUMFATHIGHMEDIUMSKULLTABLELOWSKULLTABLELOWLOWLOWDIPLOEHIGHLOWDIPLOEHIGHLOWMENINGESLOWMENINGESLOWLOWLOWVESSELLOWVESSELLOWLOWLOWCALCIFICATIONLOWCALCIFICATIONLOWLOWLOW MRIsignalintensityFrontallobePituitarybodyCentralsulcusPituitarysta
18、lkOpticchiasmGenuofcorpuscallosumMedullaoblongataClivusSphenoidsinusParietallobeThalamusOccipitallobeMamillarybodyQuadrigeminalbodyStraightsimus4thventricleCerebellartonsilGenuofcorpuscallosumFrontallobeSpleniumofcorpuscollosum3rdventricleThalamusHeadofcaudatenucleusGlobuspallidusOccipitallobeOpticr
19、adiationsSeptumpellucidumPosteriorhornoflateralventricleAnteriorhornoflateralventricleInterventricularforamenParietooccipitalsulcusThalamusHeadofcaudatenucleusGlobuspallidusOccipitallobeOpticradiationsAnteriorhornoflateralventricleInterventricularforamen3rdventricleGenuofcorpuscallosumSeptumpellucid
20、umSpleniumofcorpuscollosumPosteriorhornoflateralventriclePosteriorlimbofinternalcapsuleGenuofinternalcapsuleAnteriorlimbofinternalcapsuleParietooccipitalsulcusParietallobeSuperiortemporalgyrusMiddletemporalgyrusPonsMedullaoblongataCerebralpeduncleCentrumsemiovale3rdventricleInferiortemporalgyrusPetr
21、ousridgeoftemporalboneParahippocampalgyrusAnteriorhornoflateralventricleLateralfissureSuprasellarcisternPituitarybodyTemporallobeInerhemispericfissurecisternCorpuscallosumcaudatenucleusglobuspallidus,putamenOpticchiasmPituitarystalkCavernoussinusDSAmanifestationNormalcerebralartery(anteriorandmiddle
22、cerebralartery)graduallytaperoffwithsymmetricbranchesandsmoothmargin.Thearterieshaveinvariablelocationandcorrespondingbraintissue.Imageologicdiagnosisofthecommondisease(一)(一)BraintumorshavecommoncharacteristicinimageologicmanifestionGlioma,astrocytomaGlioma,astrocytomaMeningiomaMeningiomaPituitarytu
23、morPituitarytumorAcousticAcousticneuromaneuromaMetastasistumorMetastasistumor1、X-raymanifestation、IncreaseofintracranialpressureIncreaseanddeepeningofconvolutionalimpressions,separationofsutures,thinningofbones.、TumorlocationsignDestructionofskull,enlargementofthesellar,displacementofcalcification,d
24、ilationofInternalauditoryInternalauditorymeatusmeatus,pathologic,pathologiccacificationcacification2、CTmanifestation、DensityabnormalityThetumorsareslightlyThetumorsareslightlyhypodensehypodensetotoisodenseisodenseonplainscan.onplainscan.、MasseffectDisplacementofmidline,compressionandobstructionofven
25、tricle,hydrocephalus.、EdemaHypodensityaroundtumor,moresevereinmalignanttumor.、physiologicalcalcification:physiologicalcalcification:egeg:Irregularcalcificationcanbeenseenin:IrregularcalcificationcanbeenseeninOligodendrogliomaOligodendroglioma、DestructionofboneDefectofbone,decreaseddenstiy,eg:acousti
26、cneuroma、EnhancementIncreaseoftumordensity,thereisnoenhancementintheareaofnecrosisandedemaMRImanifestation、SignalabnormalityThetumorsareslightlyThetumorsareslightlyhypointensityhypointensitytotoisointensityisointensityonplainscanonplainscan、MasseffectDisplacementofmidline,compressionandobstructionof
27、ventricle,hydrocephalus、EdemaEdemaisaroundtumorwithlongT1andT2relaxingtimes.、Physiologicalcalcification:Physiologicalcalcification:、Destructionofbone、EnhancementIncreaseoftumordensity,thereisnoenhancementintheareaofnecrosisandedemaT1andT2prolongationofboneareacanbeenneartumorsHypointensityinthetumor
28、onT1WIandT2WIDSAmanifestation、MasseffectVesselsdisplacement,separation,gathering,bending,straightening、TumordyeingTumorswithsufficientbloodsupplycanbeenseen1.X-RAYPLAINFILMmanifestation(二)(二)CraniocerebralinjuryTofindthepresenceorabsenceofskullfractureandtoaccessthelocationandtypeoffracture(linearfr
29、acture,comminutedfracture,depressedfracture)IntracranialinjurycannotbeenobservedCTmanifestation、EpiduralEpiduralhematomahematoma、SubduralSubdural hematomahematoma、IntracerebralIntracerebral hematomahematoma、CerebralcontusionCerebralcontusionshowsalocalizedbiconvexhighdensityundertheinnertableGeneral
30、izedperipheralhighdensityundertheinnertableRoundorirregularhyperdensityHaemorrhageandedemaareintercurrent,producingmotleydensityMRImanifestation、ChronicepiduralChronicepiduralhematomahematomaShowsalocalizedbiconvexhighintensityundertheinnertable、ChronicChronicsubduralsubdural hematomahematomaGeneral
31、izedperipheralhighintensityundertheinnertable、ChronicChronicintracerebralintracerebral hematomahematomaChronichematomaproducingirregularhyperintensitywithringsign.(三)(三)Vasculardiseases 1 1、IntracranialaneurysmIntracranialaneurysmDSACTMRIDemonstrateroundedhighdensitylinktorelativearterywithirregular
32、sizeandsmoothmarginShowsroundedflowvoidwithsmoothmarginonT1WIandT2WIDisplaysisodensityonplainscanandroundedhyperdensityonCECT2、Intracranialvascularmalformation(Arteriovenousmalformation)DSACTMRIVeinearlyemerging,malformednidus,narrowingoffeedingartery,dilateddrainingvein.Malformedvascularnidusproduc
33、ingracemoseflowvoidwithnarrowingoffeedingartery,dilateddrainingvein.DisplaysisodensityonplainscanandroundedhyperdensemalformedvascularnidusonCECT3、cerebralinfarctionMRIIschemicinfarctionproducingsectororirregularshapewithT1andT2prolongation.Masseffectcanbeenseeninextensivecases.cerebrallacunahavebee
34、nidentifiedasinfarctionslessthan1cm.CTIschemicinfarctionproducingsectororirregularhypodensitywithblurredmargin.cerebrallacunasarenoteasytofind.四、InfectiousdiseasesSuppurativeinfection:Tuberculousinfection:Viralinfection:Patasiticinfection:Encephalitis,Brainabscess,MeningitisMeningitis,TuberculomaEnc
35、ephalitis,MeningitisCysticercosis,Schistosomiasis1、BrainabscessCT:Plainscanshowsroundhypodensitywithringlikeperipheralisodensityandedema.Thereisringenhancementoftheuniformthickabscesswall.Thecentralhyodenseareainthecavitydosenotchangeinenhancement.MRI:TheabscesshavelongT1andT2relaxationtimeswithsurr
36、oundingedema.Thereisringenhancementoftheuniformthickabscesswall.Theabscesscavityhavenotenhancement.2、cerebralcysticercosisLarvalofTaeniasoliumparasitizeinbrain.Cerebrallarvalinfestationischaracterizedbyafluid-filledcystwithamuralsoft-tissuenodule.thediseasecanbeenclassifiedaslarvallivingstage,larval
37、deathstage,calcificationstage.MultipleMultiplespotlikespotlikehigh-densitywithsimilarsizeinbrain.high-densitywithsimilarsizeinbrain.CT:CT:MRI:MRI:Accompaniedbyedema,themultiplecystswithAccompaniedbyedema,themultiplecystswithlongT1andT2signalarenomorethan1cminlongT1andT2signalarenomorethan1cmindiamet
38、er,diameter,larvallivingstage:larvallivingstage:Thelow-densitycystsoccuringroupswithThelow-densitycystsoccuringroupswithspotlikespotlike muralnodule.muralnodule.Calcificationstage:Calcificationstage:二二.NormalmanifestationExaminationofspinalcord一、一、ExaminationmethodMRICTCTMyelographyMyelographyX-rayX
39、-rayspinalcanal:11mmlong,16mmwide,Spinalcord:columniform,smoothmargin,homogeneous三、三、三、三、IntramedullaryIntramedullaryIntramedullaryIntramedullary tumor are predominantly tumor are predominantly tumor are predominantly tumor are predominantly ependymomaependymomaependymomaependymoma and and and and a
40、strocytoma.(aboutastrocytoma.(aboutastrocytoma.(aboutastrocytoma.(about 90%of all 90%of all 90%of all 90%of all intraspinalintraspinalintraspinalintraspinal tumors)tumors)tumors)tumors)TheoutlineofMRIdiagnosis1.thespinalcordisenlargedandthelesionisextensive2.Thesubarachnoidspacearoundthespinalcordis
41、narrowedorblocked3.secondarysyringohydromyelia4.ThetumorsareslightlyhypointenseonT1andslightlyhyperintenseonT2.Enhancementcanbeenseen.4 4、ExtramedullaryExtramedullary intraduralintradural tumor tumorwhichiscomposedprincipallyofmeningiomasandnervesheathtumorsTheoutlineofMRIdiagnosis1.spinalcorddispla
42、cementtothecontralateralside2.Thesubarachnoidspaceonthesideofthetumorisdilated3.Thetumorislocalizationwithclearmargin4.ThetumorisisointensityonbothT1andT2withobviousenhancement.五、五、ExtramedullaryExtramedullary extraduralextradural tumor tumorMalignantlymphomaandmetastasisisusuallyobservedTheoutlineo
43、fMRIdiagnosis4.slighthypointensityonT1andslighthyperintensityonT2,enhancementcanbeenseen.3.spinalcorddisplacementtothecontralateralsideandnarrowsubarachnoidspaceonthesideofthetumor2.Duraisshownashypointensitybetweenthetumorandspinalcord.1.Thetumorsareflatandextendtoalargearea.六、六、Spinal cord injuryS
44、pinal cord injuryTheoutlineofMRIdiagnosis1.spinalcordedema:hypointensityonT1andhyperintensituonT22.Spinalcordhemorrhage:Thesignalsevolvementwerethesamewithintracerebralhematoma.3.Spinalcordtransectioninjury:thespinalcordsignalsareinterrupted.4.Spinalcordintenerate:hypointensityonT1andhyperintensituonT2ThevertebralcolumnandspinalcordinjuryTheinjuryconsistsoffractureofvertebralbodyandappurtenance,spinalcordconcussion,spinalcordcontusionspinalcordcompression,spinalcordtransverseinjuryandhematoma,nervenerverootsavulsion,rootsavulsion,spinalcordintenerateandsoon.MRIisthefirstofchoice.谢谢