英文演讲-高尿酸血症.ppt

TheThelargest killerlargest killerlargest killerlargest killerfourthfourthfourthfourthhyperglycemiahyperglycemiahyperlipidemiahyperlipidemiahypertensionhypertensionHyperuricemiaHyperuricemiaThe definition of The definition of lMen:serum uric acid more than 420mmol/L lWomen:serum uric acidmore than 360mmol/L We can define as hyperuricemiaWe can define as hyperuricemia.In the normal purine diet condition,we test the fasting In the normal purine diet condition,we test the fasting uric acid not on the same day.uric acid not on the same day.hyperuricemia hyperuricemia What is tWhat is the harm of hyperuricemia?he harm of hyperuricemia?introduction of the goutintroduction of the gout Elevated uric acid Elevated uric acidgouty arthritisgouty arthritisdysarthrosisdysarthrosisdepositedeposited ind in the the jointsjointsH HyperuricemiayperuricemiaOther metabolic syndromes Other metabolic syndromes uric acid stoneuric acid stonemicroangiopathymicroangiopathy Elevated uric acid Elevated uric acidRenal damageRenal damagedeposition in deposition in the kidneythe kidneyinferent inferent arteriolearterioleatherosisatherosisElevated uric acidElevated uric acid stimulation stimulation to vesselto vesselstimulatestimulate renin secretion renin secretionactivate activate RAS systemRAS system hypertension hypertension hypertension hypertension aggravate aggravatehypertensionhypertensiondecreaseddecreasedexcretion abilityexcretion abilityhyperuricemiahyperuricemia impairment in impairment in kidney function kidney function1.Mazali M,Hughes J,Kimy C.1.Mazali M,Hughes J,Kimy C.Elevatet Uric Acid increaser Elevatet Uric Acid increaser blood pressure in the rat by a novel cryatlin-drpendent blood pressure in the rat by a novel cryatlin-drpendent mechanismJ.Hypertension,2001,(05):1101-1106.mechanismJ.Hypertension,2001,(05):1101-1106.2.Khosla U M,Zharikov S,Finch J L.2.Khosla U M,Zharikov S,Finch J L.Hyperuricemia induces Hyperuricemia induces endothelial dysfunctionJ.Kidney International,2005.1739-endothelial dysfunctionJ.Kidney International,2005.1739-1742.1742.Elevated uric acidElevated uric acidInsulin Insulin resistanceresistanceinduce or aggravate diabetesinduce or aggravate diabetes1.Uyarel H,Hergenc G.1.Uyarel H,Hergenc G.Serum uric acid is a Serum uric acid is a determinant of metabolic syndrome in a population based determinant of metabolic syndrome in a population based study J.American Journal of study J.American Journal of Hypertension,2006,(10):1055-1062.Hypertension,2006,(10):1055-1062.damagedamagepancreaticpancreaticcellscells1.Available study suggests that hyperuricemia appears 1.Available study suggests that hyperuricemia appears to potentially contribute to obesity,hypertension,to potentially contribute to obesity,hypertension,diabetes,renal and cardiovascular diseases.diabetes,renal and cardiovascular diseases.2.The uric acid is one of the important markers to 2.The uric acid is one of the important markers to predict these diseases.predict these diseases.3.Hence,there should be an effective implementation in 3.Hence,there should be an effective implementation in all aspects to reduce the adverse effects of uric acid all aspects to reduce the adverse effects of uric acid in metabolic syndrome.in metabolic syndrome.In conclusionIn conclusion 后面内容直接删除就行后面内容直接删除就行资料可以编辑修改使用资料可以编辑修改使用资料可以编辑修改使用资料可以编辑修改使用主要经营：网络软件设计、图文设计制作、主要经营：网络软件设计、图文设计制作、发布广告等发布广告等公司秉着以优质的服务对待每一位客户，做公司秉着以优质的服务对待每一位客户，做到让客户满意！到让客户满意！致力于数据挖掘，合同简历、论文写作、致力于数据挖掘，合同简历、论文写作、PPTPPT设计、计划书、策划案、学习课件、各设计、计划书、策划案、学习课件、各类模板等方方面面，打造全网一站式需求类模板等方方面面，打造全网一站式需求The user can demonstrate on a projector The user can demonstrate on a projector or computer,or print the presentation or computer,or print the presentation and make it into a film to be used in a and make it into a film to be used in a wider fieldwider field