1、文档仅供参考,不能作为科学依据,请勿模仿;如有不当之处,请联系网站或本人删除。Sexually transmitted disease,STDvSTD is used to denote disorders spread principally by sexual intercourse or behavior similar to that.vForms of transmission:Sexual transmissionIndirect contact transmission blood touchiatrogenic(医源性)transmission文档仅供参考,不能作为科学依据,请
2、勿模仿;如有不当之处,请联系网站或本人删除。STD surveillanceSTD surveillance in ChinavvSyphilis Syphilis vvGonorrhea Gonorrhea vvAIDS AIDS vvNongonococcal urethritis(NGU,Nongonococcal urethritis(NGU,非淋菌性尿道炎非淋菌性尿道炎)vvCondyloma acuminata(Condyloma acuminata(尖锐湿疣尖锐湿疣)vvChancroid(Chancroid(软下疳软下疳)vvLymphogranuloma venereum(L
3、ymphogranuloma venereum(性病性淋巴肉芽肿性病性淋巴肉芽肿)vvGenital herpes(Genital herpes(生殖器疱疹生殖器疱疹)Sexually transmitted disease,STD文档仅供参考,不能作为科学依据,请勿模仿;如有不当之处,请联系网站或本人删除。Sexually transmitted disease,STDPathogens:vBacteriavVirusvSpirochete(螺旋体)vMycoplasmavChlamydiavProtozoa(原虫)vFungi(真菌)vEctoparasite(寄生虫)文档仅供参考,不能作
4、为科学依据,请勿模仿;如有不当之处,请联系网站或本人删除。Sexually transmitted disease,STD Gonorrhea vPathogen:Neisseria gonorrhoeaevTransmission:primarily by sexual contactvInvasion:columnar epithelium and transitional epithelium cervix,urethra upper reproductive tract文档仅供参考,不能作为科学依据,请勿模仿;如有不当之处,请联系网站或本人删除。GonorrheaClinical fi
5、ndings:Incubation period:1-10 days50%70%patients are asymptomatic.1.Lower genital tract infection:endocervicitis urethritisbartholinitis(前庭大腺炎)2.Upper genital tract infection:pelvic inflammatory disease(PID)3.Disseminated gonococcal infection(DGI)pass by blood circulation文档仅供参考,不能作为科学依据,请勿模仿;如有不当之处,
6、请联系网站或本人删除。Gonorrhea文档仅供参考,不能作为科学依据,请勿模仿;如有不当之处,请联系网站或本人删除。Diagnosis:According to bad sexual encounter,clinical findings and laboratory findingsGram-negative diplococci(双球菌)can be seen microscopically in secretions.Culture is the best standard.PCRGonorrhea文档仅供参考,不能作为科学依据,请勿模仿;如有不当之处,请联系网站或本人删除。Treat
7、ment:Principles:promptly、full dose、antibiotics availablevthird generation cephalosporinsvquinolones Criterion of cure:Under the situation of no sexual life and 2 weeks after the whole therapy,the clinical symptoms and signs have gone.The 4-7d after cure,the smear testing and culture of secretion in
8、cervical canals are negative.Gonorrhea文档仅供参考,不能作为科学依据,请勿模仿;如有不当之处,请联系网站或本人删除。Sexually transmitted disease,STD SyphilisvPathogen:Treponema pallidum vTransmission:sexually transmissionindirect contact transmission blood touchfrom infected mother to fetus文档仅供参考,不能作为科学依据,请勿模仿;如有不当之处,请联系网站或本人删除。SyphilisC
9、linical findings:1.Primary syphilis:chancre(硬下疳)indurated,firm,painless papule or ulcer with raised borders on labia,vulva,vagina,cervix,anus,lips,or nipples2.Secondary syphilis:diffuse bilaterally symmetric extragenital papulosquamous eruption(丘疹鳞屑性皮疹),condyloma latum(扁平湿疣)3.Tertiary syphilis:cardi
10、ac,neurologic(神经的),ophthalmic(眼的),and auditory(耳的)lesions文档仅供参考,不能作为科学依据,请勿模仿;如有不当之处,请联系网站或本人删除。Syphilissecondary syphilisvcondyloma latum(扁平湿疣)secondary syphilis:vpapulosquamous (丘疹疹鳞屑性皮疹)文档仅供参考,不能作为科学依据,请勿模仿;如有不当之处,请联系网站或本人删除。SyphilisTertiary syphilis文档仅供参考,不能作为科学依据,请勿模仿;如有不当之处,请联系网站或本人删除。Syphilis
11、Laboratory findings:1.Identification of the organism Darkfield microscopy examination(暗视野显微镜检查)Treponema pallidum(梅毒螺旋体)2.Serologic examination a.Nontreponemal tests(非梅毒螺旋体抗原试验)VDRL,RPR syphilis screening(筛查)b.Treponemal tests(梅毒螺旋体抗原试验)TPPA,TPHA syphilis confirmation(确诊)3.Examination of cerebrospin
12、al fluid(脑脊液脑脊液)文档仅供参考,不能作为科学依据,请勿模仿;如有不当之处,请联系网站或本人删除。SyphilisTreatment:penicillinCriterion of cure:Clinical cureSerologic cure文档仅供参考,不能作为科学依据,请勿模仿;如有不当之处,请联系网站或本人删除。Sexually transmitted disease,STD Condyloma acuminata (尖锐湿疣)(尖锐湿疣)vPathogen:human papilloma virus(HPV)mainly Types 6 and 11 low-risk H
13、PVvTransmission:sexually transmission文档仅供参考,不能作为科学依据,请勿模仿;如有不当之处,请联系网站或本人删除。Condyloma acuminata Clinical FindingsSymptomsneoplasm:vulvae,cervix,vagina,perianal area(肛周)vulvar pruritusvulvar burning sensationpostcoital bleedingSigns:Tiny,isolated or clustering pink papules(丘疹)are present at first,the
14、n get together just like comb shape(鸡冠状).文档仅供参考,不能作为科学依据,请勿模仿;如有不当之处,请联系网站或本人删除。Condyloma acuminata文档仅供参考,不能作为科学依据,请勿模仿;如有不当之处,请联系网站或本人删除。Condyloma acuminata Laboratory Findings Cytology:koilocytosis(挖空细胞)dyskeratosis(角化不良细胞)parakeratosis(角化不全细胞)Acetic acid test(醋酸试验)white(+)Colposcope(阴道镜)Pathology
15、:hyperplasia of squamous epitheliumPCR:HPV detect文档仅供参考,不能作为科学依据,请勿模仿;如有不当之处,请联系网站或本人删除。Condyloma acuminata TreatmentThere is no cure for HPV although lesions can be removed.nExternal medicine Podophyllin(0.5%足叶草脂毒素酊,鬼臼毒素).Trichloroacetic acid(50%三氯醋酸)nPhysical therapy Microwave Laser therapy CryotherapynExcisionnInterferon LOGO