生物化学与分子生物学PPT图片素材-ScienceSlide2.ppt

CholesterolSterol ToolkitPregnenolonProgesteronAldosteronCortisolCorticosteroneAndrostendioneTestosteronEstriol17-Estradiol1,25-DihydroxycholecalciferolCholic acidCovalent modification of proteinsPoly(ADP ribosyl)Polymerase(PARP)Poly(ADP ribosyl)polymerase(PARP)NADNicotinamidePoly(ADP ribosyl)polymerase(PARP)Poly(ADP ribosyl)chain elongationand branchingNicotinamideNADNADDNA polymerase DNA polymerase DNA polymerase OligosacharyltransferaseN-glycosylation pathway in ERMann-P-DolicholtransferasesFlippaseDolicholPDolicholPPDolicholPPDolicholPPDolicholPPGlcNAc-PtransferaseGlcNActransferaseDolicholPDolicholPPDolicholPPGDP-Mannosyl transferasesGlc-P-DolicholtransferasesDolicholPDolichol-pyrophofphataseCytosolER40S60SUTPCTPTMPPyrimidine Nucleotide InterconversionsUMPATPADPH2OUDPNucleosidemonophosphatekinaseATPADPNucleosidediphosphatekinaseATPADPCTPsynthaseRibonucleotidereductasedeoxyUDPNucleosidediphosphatephosphohydrolasedeoxyUMPThymidylatesynthaseN5,N10-MethyleneTHFDHFTTPNucleosidemonophosphatekinaseNucleosidediphosphatekinaseMyo-Inositol-3-phosphateIns(3)P1Biosynthesis and metabolism of phosphoinositidesGlucose 6-pgosphateIns(3)P1synthaseIns(3)P1phosphataseMyo-InositolInsPtdInssynthasePtdInsMyo-inositolkinasePtdIns-4-PPtdIns4-kinasePtdIns5-kinasePtdIns-4,5-P2PI3KPtdIns-3,4,5-P3PLCPLCPI3KPtdIns-3,4-P2Ins-1,3,4-P3Ins-1,3,4,5-P4Ins-1,4,5-P3PLCPTENPTENIns-1,4-P3PTENPTENFatty acidsynthase-ketoacylACP-synthaseFatty acids synthesisAcetyl CoAcarboxylaseATPADP+PiAcetyl CoAMalonyl CoACitrateOxaloacetateATPADP+PiCitrate lyaseAcetyltransacylaseMalonyltransacylasePantetheine-ketoacylACP-reductasePantetheinePantetheine-hydroxyacylACP-dehydratasePantetheineEnoyl-ACPreductasePantetheineNADPHNADPNADPHNADPCholesterol de novo synthesis IIsoprenyl formationAcetoacetyl-CoAThiolaseHMG-CoAsynthaseMevalonate3-Hydroxy-3-methylglutaryl-CoAMevalonatekinasePhosphomevalonatekinaseMevalonate-5-pyrophosphodecarboxylase5-Phosphomevalonate5-Pyrophosphomevalonate3-Isopentenylpyrophosphate3,3-DimethylalylpyrophosphateIsomeraseHMG-CoAreductase2 NADPH2 NADPATPADPADPATPADPATPCholesterolBiosynthesis of bile acids7-HydroxycholesterolSterol 7 hydroxylaseCYP7A17-Hydroxy-4-cholesten-3-one3-Hydroxystroid dehydrogenaseHSD3B77,12-Dihydroxy-4-cholesten-3-oneSterol-12-hydroxylaseCYP8B15-Cholestan-3,7,12-TriolOxosteroid-5-reductaseAKR1D1Sterol 27-hydroxylaseCYP27A13,7,12-Trihydroxy-5-cholestanoic acidCholic acidAKR1D1AKR1C45-Cholestan-3,7-diol12-Deoxycholic acid3-Hydroxy-steroid dehydrogenaseAKR1C4Biosynthesis of RNARNAPolymeraseBiosynthesis of DNADNAPolymerase-oxidationMitochondrial matrixIntermembranespacePalmitoyl carnitinePalmitoyl carnitinePalmitoyl CoAPalmitoyl CoATrans 2 enolopalmitoyl CoA3-Hydroxypalmitoyl CoA3-Ketopalmitoyl CoAMyristoyl CoAAcetyl-CoAPalmitoyl CoAPalmitatePalmitoyl CoAligaseATPAMPCarnitineacyltransferase ICarnitineCarnitineacyltransferase IIAcyl CoAdehydrogenaseEnoyl CoAhydratase3-Hydroxyacyl CoAdehydrogenaseCitric AcidCycleFADFADH2NADNADHCytoplasmH2OMyo-Inositol-3-phosphateIns(3)P1Phospho-myo-inositol Toolkit 2Myo-Inositol-3,4-diphosphateIns(3,4)P2Myo-Inositol-3,6-diphosphateIns(3,6)P2Myo-Inositol-3,4,6-triphosphateIns(3,4,6)P3Myo-Inositol-1,3,4-triphosphateIns(1,3,4,)P3Myo-Inositol-3,4,5,6-tetraphosphateIns(3,4,5,6)P4Myo-Inositol-1,4,5-triphosphateIns(1,4,5)P3Myo-Inositol-1,3,4,6-tetraphosphateIns(1,3,4,6)P4Myo-Inositol-1,3,4,5-tetraphosphateIns(1,3,4,5)P4Myo-Inositol-1,4,5,6-tetraphosphateIns(1,4,5,6)P4Myo-Inositol-1,2,3,4,6-pentaphosphateIns(1,2,3,4,6)P5Myo-Inositol-1,3,4,5,6-pentaphosphateIns(1,3,4,5,6)P5Myo-Inositol-1,2,3,4,5-pentaphosphateIns(1,2,3,4,5)P5Myo-Inositol-1,2,4,5,6-pentaphosphateIns(1,2,4,5,6)P5Myo-Inositol-1,2,3,4,5,6-hexaphosphateIns(1,2,3,4,5,6)P6 (Phytic acid)Myo-Inositol-3-phosphateIns(3)P1Phospho-myo-inositol ToolkitMyo-Inositol-3,4-diphosphateIns(3,4)P2Myo-Inositol-3,6-diphosphateIns(3,6)P2Myo-Inositol-3,4,6-triphosphateIns(3,4,6)P3Myo-Inositol-1,3,4-triphosphateIns(1,3,4,)P3Myo-Inositol-3,4,5,6-tetraphosphateIns(3,4,5,6)P4Myo-Inositol-1,4,5-triphosphateIns(1,4,5)P3Myo-Inositol-1,3,4,6-tetraphosphateIns(1,3,4,6)P4Myo-Inositol-1,3,4,5-tetraphosphateIns(1,3,4,5)P4Myo-Inositol-1,4,5,6-tetraphosphateIns(1,4,5,6)P4Myo-Inositol-1,2,3,4,6-pentaphosphateIns(1,2,3,4,6)P5Myo-Inositol-1,3,4,5,6-pentaphosphateIns(1,3,4,5,6)P5Myo-Inositol-1,2,3,4,5-pentaphosphateIns(1,2,3,4,5)P5Myo-Inositol-1,2,4,5,6-pentaphosphateIns(1,2,4,5,6)P5Myo-Inositol-1,2,3,4,5,6-hexaphosphateIns(1,2,3,4,5,6)P6 (Phytic acid)GlycogenGlycogenin8-oxoguanineA common DNA lesions Toolkit IO6-methylguanineUracilThymine glycol1,N6-ethenoadenine3-methyladenineCyclobutane pyrimidine dimersPhotoadductRiboseGlucuronateArabinoseFructoseGlucoseGalactoseMannoseFucoseSialic AcidInositolD-AbequoseL-RhamnoseA carbohydrate toolkitPGH2TXA2TXB2Bioactive lipids-ProstanoidsPGD2PGJ2PGE2PGA2PGB2PGF2PGF-MPGI26-keto-PGF1 Bioactive lipids-Leukotrienes5-HETELTA4LTB4LTC4LTD4LTE420-OH-LTE4LXA4LTB4LTF4LXALXBBioactive lipidsArachidonateCeramideSphingosine-1-phosphatePAFPhosphatidic acidAnandamide 2-Arachidonoylglycerol