生物化学ATP的计算.pptx

单击此处编辑母版标题样式,单击此处编辑母版文本样式,第二级,第三级,第四级,第五级,*,谷氨酸脱氨后彻底氧化为,CO,2,和,H,2,O,净生成多少个,ATP,？写出代谢历程,。,谷氨酸,NAD(P),+,+H,2,O a-,酮戊二酸,+NH,3,+NAD(P)H,a-,酮戊二酸 草酰乙酸（,FADH2+2NADH+GTP,）,草酰乙酸,+,GTP,PEP+GDP+CO,2,PEP+ADP,丙酮酸,+ATP,丙酮酸,+NAD,+,+CoASH,乙酰,CoA+NADH+H,+,+CO,2,乙酰,CoA+3NAD,+,+FAD+GDP+Pi+2H,2,O,2CO,2,+CoASH+3NADH+3H,+,+FADH,2,+GTP,1GTP=1ATP,（,1,）共消耗,1ATP,，生成,3ATP,、,7NADH,和,2FADH,则净生成：,-1+3+2.57+1.52,22.5ATP,（,2,）共消耗,1ATP,，生成,3ATP,、,6NADH,、,2FADH,和,1NADPH,则净生成：,-1+3+2.56+1.52,20ATP,L-,谷氨酸脱氢酶,PEP,羧激酶,丙酮酸激酶,丙酮酸脱氢激酶,TAC,TCA,循环,天冬氨酸脱氨后彻底氧化为,CO,2,和,H,2,O,净生成多少个,ATP,？写出代谢历程,。,天冬氨酸,+a-,酮戊二酸 草酰乙酸,+,谷氨酸,谷氨酸,NAD(P),+,+H,2,O a-,酮戊二酸,+NH,3,+NAD(P)H,草酰乙酸,+GTP PEP+GDP+CO,2,PEP+ADP,丙酮酸,+ATP,丙酮酸,+NAD,+,+CoASH,乙酰,CoA+NADH+H,+,+CO,2,乙酰,CoA+3NAD,+,+FAD+GDP+Pi+2H,2,O,2CO,2,+CoASH+3NADH+3H,+,+FADH,2,+GTP,1GTP=1ATP,（,1,）共消耗,1ATP,，生成,2ATP,、,4NADH,和,1FADH,则净生成：,-1+2+2.55+1.51,15ATP,（,2,）共消耗,1ATP,，生成,2ATP,、,3NADH,、,1FADH,和,1NADPH,则净生成：,-1+2+2.54+1.51,12.5ATP,谷草转氨酶,L-,谷氨酸脱氢酶,PEP,羧激酶,Mg,2+,丙酮酸激酶,丙酮酸脱氢激酶,TCA,循环,丙氨酸脱氨后彻底氧化为,CO,2,和,H,2,O,净生成多少个,ATP,？写出代谢历程,。,丙氨酸,+a-,酮戊二酸 丙酮酸,+,谷氨酸,谷氨酸,NAD(P),+,+H,2,O a-,酮戊二酸,+NH,3,+NAD(P)H,丙酮酸,+NAD,+,+CoASH,乙酰,CoA+NADH+H,+,+CO,2,乙酰,CoA+3NAD,+,+FAD+GDP+Pi+2H,2,O,2CO,2,+CoASH+3NADH+3H,+,+FADH,2,+GTP,1GTP=1ATP,（,1,）共消耗,0ATP,，生成,1ATP,、,5NADH,和,1FADH,则净生成：,1+2.55+1.51,15ATP,（,2,）共消耗,0ATP,，生成,1ATP,、,4NADH,、,1FADH,和,1NADPH,则净生成：,1+2.54+1.51,12.5ATP,谷丙转氨酶,L-,谷氨酸脱氢酶,丙酮酸脱氢酶系,TCA,循环,