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,*,单击此处编辑母版标题样式,单击此处编辑母版文本样式,第二级,第三级,第四级,第五级,单击此处编辑母版标题样式,单击此处编辑母版文本样式,第二级,第三级,第四级,第五级,*,第一节,计算机信息检索的发展,计算机信息检索是利用计算机查找出符合读者所需信息的过程。,计算机信息检索的发展史,脱机信息检索阶段,(20,世纪,50,年代中期到,60,年代中期,),联机信息检索阶段,(20,世纪,60,年代中期到,70,年代初期,),跨国联机信息检索阶段,(20,世纪,70,年代中期至今,),光盘信息检索阶段,(20,世纪,80,年代中期至今,),网络信息检索阶段(,20,世纪,90,年代至今),第二节,计算机信息检索的基础知识,CBMDISC,数据库检索结果题录格式,标题:急性胰腺炎中西医结合与单纯西医治疗对比分析,作者:陈晓东,(1);,孔棣,(2);,马明,(1),作者单位:,(1),天津医科大学研究生,天津,300070;(2),天津市南开医院,天津,300100,出处:天津中医药,2010;(2):116-117,相关链接:主题相关,CBMDISC,数据库详细记录格式,(,中文,),(,机标,),流水号,2006156553,标题,2005,年重庆市城乡高血压流行病学调查及相关因素分析,英文标题,Hypertensive epidemiological survey and correlation factors analysis in urban and rural areas of Chongqing City in 2005,著者,胡蓉,(1);,黄晓波,(1);,罗开良,(1);,胡淀,(2);,乐庆荣,(1);,侯永兰,(1);,卢仙娥,(3),著者单位,(1),重庆医科大学附属第二医院心血管内科,重庆,400010;(2),重庆医科大学医学统计学教研室,重庆,400016;(3),重庆医科大学流行病学教研室,重庆,400016,国省市名 重庆,文摘,目的,:,研究重庆市城乡人群高血压患病情况、危险因素、临床特点。,方法,:15,岁以上人群抽取,5246,人进行调查,对城乡人群各年龄段的资料进行对比研究。,结果,:,重庆市,15,岁以上自然人群高血压患病率为,18.49%(,标化率,16.65%),男性为,18.79%,女性为,18.23%,结论,:,重庆市城乡人群高血压各有其特点,防治措施必须针对改变膳食结构、加强锻炼、减重等为重点。,著者文摘,Author,参文数,6,基金,重庆市卫生局资助项目,(2003),出处,第三军医大学学报,2006;28(10),:1121-1123,ISSN1000-5404,国内代码,51-1095,内部代码,D07,出版地重庆,字段组成,PubMed:summary,格式,(,AU,),Haberl I,Frei K,Ramsebner R,Doberer D,Petkov V,Albinni S,Lang I,Lucas T,Mosgoeller,W,(,TI,),Vasoactive intestinal peptide gene alterations in patients with idiopathic pulmonary arterial hypertension.,(,SO,),Eur J Hum Genet.2006 Sep 27;Epub ahead of print,(,PMID,),17003842 PubMed-as supplied by publisher,PubMed:abstracts,格式,(,SO,),Eur J Hum Genet.2006 Sep 27;Epub ahead of print,(,TI,),Vasoactive intestinal peptide gene alterations in patients with idiopathic pulmonary arterial hypertension.,(,AU,),Haberl I,Frei K,Ramsebner R,Doberer D,Petkov V,Albinni S,Lang I,Lucas T,Mosgoeller W,.,(,AD,),1Medical University of Vienna,Department of Internal Medicine I,Division Institute of Cancer Research,Borschkegasse 8a,Vienna A-1090,Austria.,(,AB,),Pulmonary arterial hypertension is a progressive disease,characterised by increased proliferation of pulmonary artery smooth muscle cells,vasoconstriction and remodelling of the vascular wall leading to right heart failure and death.The idiopathic form is rare(idiopathic arterial primary hypertension(IPAH);formerly PPH,MIM#.untranslated region in exon 7(g.8129TC)was observed in five patients.It appeared in 46%of the control group.The frequency of this alteration in the coding region of the VIP gene could therefore not be correlated with the appearance of IPAH.Apart from the importance of VIP signalling,genetic and/or environmental modifiers might therefore contribute to the development and perpetuation of the disease.,(,SO,),European Journal of Human Genetics advance online publication,27 September 2006;doi:10.1038/sj.ejhg.5201711.PMID:17003842 PubMed-as supplied by publisher,Web of science详细格式,Vasoactive intestinal peptide gene alterations in patients with idiopathic pulmonary arterial hypertension,作者,:,Haberl,I,(Haberl,Ines);,Frei,K,(Frei,Klemens);,Ramsebner,R,(Ramsebner,Reinhard);,Doberer,D,(Doberer,Daniel);,Petkov,V,(Petkov,Ventzislav);,Albinni,S,(Albinni,Sulaima);,Lang,I,(Lang,Irene);,Lucas,T,(Lucas,Trevor);,Mosgoeller,W,(Mosgoeller,Wilhelm),来源出版物,:EUROPEAN JOURNAL OF HUMAN GENETICS,卷,:15,期,:1,页,:18-22 DOI:10.1038/sj.ejhg.5201711,出版年,:JAN 2007,被引频次,:,5,(,来自,Web of Science),引用的参考文献,:,15,查看,Related Records,摘要,:,Pulmonary arterial hypertension is a progressive disease,characterised by increased proliferation of pulmonary artery smooth muscle cells,vasoconstriction and remodelling of the vascular wall leading to right heart failure and death.The idiopathic form is rare(idiopathic arterial primary hypertension(IPAH);formerly PPH,MIM#178600).Our group correlated a deficiency in vasoactive intestinal peptide(VIP;MIM#192320)levels in serum and lung tissue with the pathogenesis of IPAH.The aim of this study was to investigate the relevance of genetic alterations in VIP to the development of IPAH.We screened 10 patients(age 4-66 years)for alterations in the coding,the noncoding regions and the enhancer region of the VIP gene by direct sequencing.In eight of 10 patients,we found alterations compared to the wild-type sequence.We detected nine alterations.In the noncoding regions,eight alterations were in the introns 1,2,3 and 4(g.448G A g.501C T g.764T C g.2267A T g.2390C T g.3144T C g.3912A G g.4857A G).In the coding regions,a single alteration in the 30 untranslated region in exon 7(g.8129T C)was observed in five patients.It appeared in 46%of the control group.The frequency of this alteration in the coding region of the VIP gene could therefore not be correlated with the appearance of IPAH.Apart from the importance of VIP signalling,genetic and/or environmental modifiers might therefore contribute to the development and perpetuation of the disease.,文献类型,:Article,语种,:English,作者关键词,:idiopathic pulmonary arterial hypertension;vasoactive intestinal peptide;gene alterations;VIP serum by RIA KeyWords Plus:POLYPEPTIDE;MICE;VIP,通讯作者地址,:Mosgoeller,W(,通讯作者,),Med Univ Vienna,Dept Internal Med 1,Div Inst Canc Res,Borschkegasse 8A,A-1090 Vienna,Austria,地址,:1.Med Univ Vienna,Dept Internal Med 1,Div Inst Canc Res,A-1090 Vienna,Austria 2.Med Univ Vienna,Dept Otorhinolaryngol,A-1090 Vienna,Austria 3.Med Univ Vienna,Dept Internal Med 4,Div Pulm Med,A-1090 Vienna,Austria 4.Med Univ Vienna,Dept Pediat,A-1090 Vienna,Austria 5.Med Univ Vienna,Dept Internal Med 2,Div Cardiol,A-1090 Vienna,Austria 6.Med Univ Vienna,Dept Histol,A-1090 Vienna,Austria,电子邮件地址,:,wilhelm.mosgoellermeduniwien.ac.at,出版商,:NATURE PUBLISHING GROUP,MACMILLAN BUILDING,4 CRINAN ST,LONDON N1 9XW,ENGLAND,JCR,类别,:Biochemistry Genetics&Heredity,学科类别,:Biochemistry Genetics&Heredity,IDS,号,:117RM ISSN:1018-4813,文献特征的字段描述,外部特征:文献外在形式的反映。如书名(题名、篇名)、人名(作者)、机构名(通信地址、作者单位)、出版社、出版时间、专利号等。(题录格式),内部特征:表征文献实质意义、反映实际内容的。如主题词、关键词、分类号、国际专利分类号、文摘等。(文摘格式),文献著录(文献特征的格式描述),文献著录总则,GB/T 3792.12009,著录:,在编制文献目录时,对文献的内容和形式特征进行分析、选择和记录的过程。,著录格式:,构成款目(记录)的各个项目(字段)在载体(物质形态)上的排列顺序。不同的表达代表不同的文献类型。,出处,:,第三军医大学学报,2006;28(10),:1121-1123,二、计算机信息检索技术,1.,布尔逻辑检索,布尔逻辑算符有“与”、“或”、“非”,分别用,AND,、,OR,和,NOT,表示。,A AND B A OR B A NOT B,例:,A=1,2,3,4,5,B=3,4,5,6,7,A AND B=A OR B=A NOT B=,3,4,5,1,2,3,4,5,6,7,1,2,逻辑与,(AND),:,含义:表示相交关系。组配不同的检索词。检出的 记录必须同时含有所有的检索词。,作用:对检索词进行限定,缩小检索范围。提高查准率。,如:超声乳化,AND,散光,逻辑或(,OR,):,含义:表示并列关系。组配具有同义或同族概念的词。如同义词、近义词、相关词等。检出的记录中至少有两个检索词中的一个。,作用:扩大检索范围,增加文献量,提高查全率。,如:膀胱癌,OR,膀胱肿瘤,逻辑非(,NOT,):,含义:表示排斥关系。所组配的两个检索词中应从第一个概念中排除第二个概念。,作用:提高专指度,缩小检索范围。,如,heart diseases not coronary arteries disease.,2.,截词检索,截词检索:利用检索词的词干或不完整词形进行检索的过程。,截词符号有,“*”、“,?”,及“”,等,各种检索系统采用不同的符号。,如:,COMPUT*,(右截词或前方一致),如果“*”代表任意个字符,则此表达式表达的单词可以为,compute,computer,computerize,computing,等单词中的任何一个。,提高查全率。,3,精确检索或词组检索,exact wording or phrase,“”,4.,限制检索:,Limit,一种辅助检索技术。将结果限制在一定范围内。通常以一种组合形式出现。如,pubmed,中的,limit,检索。,5.,精确检索与模糊检索:多用于作者字段检索。,6.,扩展检索:通过同义词表、主题词表等索引工具将检索用词的同义或近义词扩展继而形成多个检索词的逻辑或检索。,7.,智能检索:,扩展检索,8.,跨库检索:在统一检索平台上同时检索多个数据库的操作。,三、计算机信息检索步骤,1.,检索需求分析:对信息需求进行细致分析,确定检索要求及主题内容。,2.,选库:根据主题要求、主题内容的学科性质选择检索数据库。数据库一般按学科或年代分为几个子数据库,检索者还应根据检索需要选择子数据库。,3.,选择检索途径:根据主题内容选择合适的检索途径。,4.,确定检索词:将主题内容特征、形式特征转换成相对应的主题词、分类号或包含在各类型检索语言中的检索词、检索标识。,5.,确定逻辑关系:有多个检索主题时,要确定各主题之间的逻辑关系。,6.,执行检索,得到检索结果。,8.,输出:显示、打印、存盘或通过,Email,接收。一般有题录、文摘、全文等几种输出格式,由检索者选择确定。,
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