High Sensitivity Inlet System for ICP-OES&ICPMS 英文版.pdf

2 Elemental Scientific,Inc.(ESI)designs and produces a range of sample introduction systems for the determination of trace element concentrations and isotope ratios in liquid samples when u s i n g i n d u c t i v e l y c o u p l e d p l a s m a i n s t r u m e n t a t i o n (I C P).ICP-OES and ICP-MS instruments measure most of the elements in the periodic table and are used daily by many laboratories as a routine analytical tool.ESI has many products based upon improving the efficiency and capabilities of the ICP sample introduction system.ESI has sample introduction systems for a wide range of applications,including semiconductor pure chemicals,environmental,clinical,organic solvents,isotope ratio,and many other types of trace metal determinations.Custom Products We welcome the opportunity to manufacture special products and to work with prototype designs.If you require a product not listed in the catalog,please call or email and a representative will be happy to discuss your requirements.to discuss your requirements.Elemental Scientific,Inc.Phone:[phone] Fax:[phone] Email: Elemental Scientific Inc.2440 Cuming St.Omaha,NE 68131 USA The Apex is a fully integrated inlet system that connects directly to the ICP torch injector and incorporates ESIs MicroFlow PFA or PolyPro nebulizer technology.The Apex improves sensitivity primarily by increasing both sample transport efficiency and the quality of aerosol introduced to the ICP instrument.Liquid samples are nebulized with the MicroFlow nebulizer into a heated cyclonic spray chamber and Peltier cooled condenser.This gives unsurpassed stability along with enhancements in sensitivity of between 3 10 times depending on the volume of sample introduced.APEX Sample Inlet System a high stability,high sensitivity,low-memory desolvating inlet system for ICP-OES&ICP-MS Apex Q Sample Inlet System 3 Unique patent pending flow path design ensures rapid wash out characteristics.Utilizes PFA MicroFlow or PolyPro-ST nebulizers to generate sample aerosol.Excellent signal stability Can operate from 10L/min-800L/min.Available in 4 different platforms with flow paths in Pyrex,quartz,&PFA.Can tolerate samples with high TDS.Small footprint.O-ring free to give low backgrounds.Integrated 4 channel peristaltic drain pump Can be used with or without membrane desolvation.Two optional membrane units available,ACM cooled Nafion membrane and Spiro heated Teflon membrane The 4 available Apex platforms are:Apex E -Low cost unit designed primarily for ICP Emission systems.The sample path is made from Pyrex and temperature settings of the heater and chiller are fixed.Apex Q -Has an o-ring-free Quartz flow path for high sensitivity and low background for samples that do not contain hydrofluoric acid.The Apex Q gives the fastest rinse-out of any high sensitivity ICP introduction system.Apex HF-Uses a high-purity PFA Teflon flow path to provide resistance to HydroFluoric acid.Apex IR-Has a quartz flow path and includes an additional mixing chamber giving the most stable signal,ideal for Isotope Ratio analysis.4 Peltier-Cooled Multipass Condenser 2C/-5C N2 Port To ICP Heated Cyclonic SC(120C/140C)Condenser Loop PFA-Nebulizer Additional Gas Inlet Waste Sample Flow Path The unique patent pending,o-ring free,sample flow path is constructed entirely from 3 different materials to suit every laboratories application and cost needs.The sample is aspirated via a PFA MicroFlow Internal sample flow path of the Apex sample inlet system.nebulizer into a heated cyclonic spray chamber to vaporize the entire sample.The excess solvent aerosol is then condensed out by a Peltier cooled condenser.The dry aerosol containing over 90%of the sample analyte passes to the ICP.5 Hour Signal Stability 50 ppt020000040000060000080000010000001200000050100150200250300Time(min)Signal Intensity(cps)59Co 1.3%RSD115In 0.8%RSD140 Ce 0.8%RSD238U 0.8%RSD5 Hour Signal Stability 50 ppt0200000400000600000800000100000012000005 Hour Signal Stability 50 ppt020000040000060000080000010000001200000050100150200250300Time(min)Signal Intensity(cps)59Co 1.3%RSD115In 0.8%RSD140 Ce 0.8%RSD238U 0.8%RSDUnsurpassed Stability Enhanced stability,which can be further improved with the use of the Apex IR or the addition of the ACM to the other Apex platforms.0100000002000000030000000400000005000000060000000Li7(LR)Co59(LR)In115(LR)Ba138(LR)Ce140(LR)U238(LR)Std InletApex QEnhanced Sensitivity Improvements in sensitivity that can range from 3x to 15x over standard inlet systems depending on the sample flow rate used.The Apex is over 90%efficient at transporting the sample analyte to the plasma.238U(LR)02000000400000060000008000000urine001urine002urine003urine004urine005urine006urine007urine008urine009urine010cpsMatrix Tolerance Capable of running with high matrix samples such as 10%Urine,giving 3.2%rsd after 10 x 5 min sample replicates Rapid Rinse Out The patent pending design of the sample flow path ensures minimal memory effects with rinse-outs comparable if not faster than simple cyclonic systems,even with initial higher count rates.Se Flow Injection02000400060008000100000100200300400500600Time(secs)CountsApexstandard050100545555565575585595Time(secs)Counts Performance Characteristics 5 A low cost unit designed primarily for ICP Emission systems.The sample path is made from Pyrex and temperature settings of the heater and chiller are fixed.ICP-OES detection limits can be improved by up to a factor of 6-10 when operating at 0.8 ml/min using a MicroFlow PFA-ST or PolyPro-ST nebulizer together with the Apex E.Alternatively,the combination of a low flow nebulizer with the Apex E maintains ICP-OES sensitivity while reducing sample consumption by a factor of 5-10,improving ICP-OES determinations when the volume of sample is limited.Lower cost high performance inlet system O-ring free Pyrex flow path Flow rates 100L/min0.8mL/min 610 fold enhancement in sensitivity Simple one switch control Wavelength scans from a radial ICP-OES of 10ppm solution of Arsenic and Lead introduced with both standard cyclonic spray chamber and the Apex E sample inlet system.Arsenic Lead Apex E for ICP-OES 6 Features an o-ring-free Quartz flow path for high sensitivity and low background for samples that do not contain hydrofluoric acid.The Apex Q sample path design,ensures rapid rinse-out of any high sensitivity ICP introduction system.Improves sensitivity 310 fold depending on flow rate Flow rates from 20600L/min Dual preset temperature settings for heater(105C/140C)and cooler(-5C/2C)Capable of processing volatile samples Tolerates high dissolved solids Nitrogen addition control Rapid rinse out 0100000002000000030000000400000005000000060000000Li 7Co 59In 115Ce 140U 238Ba 138IntensityStd.Inlet 100L/minApex 100L/minApex 480L/minThe Apex Q is over 90%efficient at transporting the sample analyte to the plasma.7 Apex Q-Quartz Inlet System Developed for Isotope Ratio analysis,the Apex IR has a quartz flow path and includes an additional mixing chamber that further homogenizes and stabilizes the sample aerosol stream,resulting in a more stable signal from the ICP-MS.Improves sensitivity 310 fold depending on sample flow rate Enhanced stability O-ring free Quartz sample flow path Flow rates from 20600L/min Nitrogen addition control Retrofit to Apex Q version Sr Ratios(NBS 987)Standard Error(abs.)x 10-6 SIS/PFA-50 Apex IR/PFA-100 200 ppb 10 ppb 100 ppb 84Sr/86Sr*15.3 25.8 2.8 87Sr/86Sr*3.9 7.8 2.7 88Sr/86Sr 123 111 49.8*Ratio normalized to 88Sr/86Sr Thermo Neptune 8 Apex IR for Isotope Ratio Analysis Uses a high-purity o-ring free PFA Teflon flow path to provide resistance to Hydrofluoric acid.The Apex HF is recommended for many geochemistry and semiconductor applications where samples containing HF are analyzed.Improves sensitivity 37 fold depending on flow rate Supplied with PFA MicroFlow nebulizers for minimum spiking and rapid rinse out Minimal static effects HF resistant PFA Teflon sample flow path Flow rates from 20400L/min Nitrogen addition control Mg(24)In(115)Ba(138)Ce(140)Pb(208)CrossFlow 10091 27470 26366 21499 12885 Apex HF 207329 265083 302756 246960 183914 Sensitivity comparison(1g/L)Apex HF vs.Crossflow Nebulizer Elan DRC II The Apex HF is over 90%efficient at introducing analyte to the plasma,resulting in dramatic improvements in sensitivity.9 Apex HF for Hydrofluoric Acid Resistance The Apex high efficiency sample inlet system has within it Peltier desolvation.Many applications require the removal of further solvent and matrix components of a sample than the Apex alone is capable of.Membrane desolvation can be used to increase the aerosol drying capability of the Apex system.Two membrane units are available for use with any Apex sample introduction system.ACM Cooled Micro-Porous Nafion membrane.Desolvation of small polar solvents.Allows analysis of volatile Species,no loss of analytes.Use Ar or N2 as sweep gas.Obtain CeO+:Ce+ratio of approximately 0.06%.Spiro TMD Heated Macro-Porous Teflon membrane.Desolvation of Aqueous&Organic Solutions.Run samples with high TDS.Can be used without the Apex for stand alone desolvation.Obtain CeO+:Ce+ratio of approximately 0.03%.Percentage Cerium Oxide formation for sample inlet systems on Thermo Element2.3.50.80.060.0301234CeO+/Ce+(%)Standard ScottApex HFApex HF+ACMApex HF+SpiroMembrane desolvation modules attach quickly and easily to the Apex outlet Membrane Desolvation Spiro TMD heated membrane desolvation module ACM Module cooled membrane desolvation unit 10 ACM Module Aqueous solutions and small polar organic solvents only Simple to use,sweep gas does not affect ICP tuning Lower running costs,Nitrogen can be used as the sweep gas.Can be used to analyzed volatile analytes such as Hg,B etc.Spiro TMD Module Aqueous and organic solutions can be desolvated,ideal for HPLC applications.Sweep gas does affect ICP tuning,therefore must use Argon.Removes all volatile species,i.e.SiF6 from semiconductor industry samples.Add membrane desolvation to standard 3 hour stability study running 98%Methanol through an Apex Q with Spiro TMD desolvation.High resolution scan of Spiro TMD desolvation unit used with the Apex Q,dramatically reduces matrix interferences.Reduced oxide formation using ACM Microporous Membrane Desolvator with Finnigan Element2 ICPMS.Membrane temperature=-5C Ce+CeO+CeO+/Ce+Rinse out of five orders of magnitude using ESI Apex-ACM High Sensitivity Desolvation System Apex with ACM Rinse-Out Time(sec)Log Intensity 100,000 x rinse out start rinse 238U+2 3 4 5 6 7 8 9 100 200 300 400 500 115In+11 Which Membrane?ES-4300-0000 Apex Q ES-4400-0000 Apex HF ES-4500-0000 Apex IR ES-4800-0000 Apex E ES-4599-3000 Spiro TMD Module ES-4599-2000 ACM Module Phone:[phone] Fax:[phone] Email: Elemental Scientific Inc.2440 Cuming St.Omaha,NE 68131 USA 12 Technical Specifications Ordering Information Standard Nebulizers PFA-100,PFA-ST (PolyPro-ST supplied with Apex E)Other nebulizers may be specified Nebulizer Gas Flow Rate 0.61.1 L/min Sample Uptake Rate 10-800 L/min Operating Environment Temperature 15C 30C Humidity 35 85%RH Non-condensing Heater Settings 1=100C;2=140C (Apex E preset to 140C)Chiller Settings 1=-3C;2=+2C(Apex E preset to+2C)Drain Pump 4 channel Peristaltic Pump(included)Power Requirements 12V DC power supply(included)100-240VAC,3.2A(included)Input delivering VDC,10A to instrument Dimensions(h x w x d)23cm(9”)x 12.1cm(5.75”)x 24.1cm(9.5”)Weight 3.2kg (7lbs)APEX Chiller Setting+3C Power Requirements 12V DC power supply(included)100-240VAC,3.2A(included)Input delivering VDC,10A to instrument Dimensions(h x w x d)14cm(5.5”)x 12.7cm(5”)x 8.3cm(3.25”)Weight 1.7kg(3.75lbs)Heater Setting 160C Power Requirements 12V DC power supply(included)100-240VAC,3.2A(included)Input delivering VDC,10A to instrument Dimensions(h x w x d)15.2cm(6”)x 15.2cm(6”)x 17.1cm(6.75”)Weight 1.7kg(3.75lbs)ACM SPIRO