糖代谢途径.ppt

Glucose G6PHexokinaseATP ADP Phosphoglucose insomeraseF6PPhosphofru-ctokinaseF-1,6-BPAldolaseG3P Triose phosphate isomeraseGlyceraldehyde3-phosphatedehydrogenase1,3-BPGATP ADP Phosphoglycerate kinaseADP 3-PGPi+NAD+NADHATPNADPX22-PGPhosphoglycerate mutaseEnolaseH2OPEPADP ATPPyruvate kinasePyruvate2XGlucolysis葡萄糖 葡萄糖-6-磷酸己糖激酶ATP ADP 磷酸葡萄糖 变位酶果糖-6-磷酸磷酸果糖激酶果糖-1,6-二磷酸甘油醛-3-磷酸 烯醇化酶甘油醛-3-磷酸 脱氢酶1,3-二磷酸甘油酸ATP ADP ADP 甘油酸-3-磷酸Pi+NAD+NADHATP二羟丙酮磷酸2X甘油酸-2-磷酸磷酸甘油酸 变位酶烯醇化酶H2O磷酸烯醇式 丙酮酸ADP ATP丙酮酸磷酸果糖激酶磷酸甘油酸激酶丙酮酸激酶糖代谢流程图gluconeogenesis五：丙酮酸异生作用通过哪些反应来避开合成过程中的3步不可逆反应？所需哪种酶催化？发生部位？所需能量？1.H2O+G6P Pi+Glucose occurrence:liver and kidneyG6P-ase2.F-1,6-BP+H2O Pi+F6P occurrence:cytoplasmF-1,6-2BP-ase3.Pyruvate+ATP+CO2 ADP+Pi+Oxaloacetate PyruvateCarboxylase Oxaloacetate+GTP GDP+CO2+PEP CarboxykinasePEPoccurrence:mitochondrionTotal energy consumption of the 3 steps:4 ATPs and 2 GTPs,6 high energy phosphate bonds in total.乙酰-CoANADH CO2 CO2NADH GTP H2ONADH柠檬酸合酶乌头酸酶乌头酸酶异柠檬酸脱氢酶-酮戊二酸脱 氢酶复合体琥珀酰-CoA合成酶琥珀酸脱氢酶延胡索酸酶苹果酸脱氢酶三三羧酸循酸循环Acetyl-CoANADH CO2NADH GTP H2ONADHCitrate synthaseAconitaseIsocitrate dehydrognase-KetogluteratedehydrogenasecomplexSuccinyl CoAsynthaseSuccinyl dehydrogenaseFumaraseMalate dehydrogenaseCitric Acid Cycle CO2此课件下载可自行编辑修改，供参考！感谢您的支持，我们努力做得更好！