1、Main sectionsMain sectionsCover letterCover letterFollow-up CorrespondenceFollow-up Correspondence(催稿信)(催稿信)Revised Manuscript Revised Manuscript(稿件退修稿件退修)1 11.How to write a cover1.How to write a cover letterletterkeep it simple and professional.keep it simple and professional.Your cover letter sho
2、uld be prepared in a standard business Your cover letter should be prepared in a standard business format(block or modified block).format(block or modified block).2 22.The informations in a Cover Letter 2.The informations in a Cover Letter(1)The correspondence information of the correspondent;(1)The
3、 correspondence information of the correspondent;(2)The title of the manuscript,the numbers of tables,figures,(2)The title of the manuscript,the numbers of tables,figures,charts,plates and so on;charts,plates and so on;(3)The statement that this manucript has never been partly or(3)The statement tha
4、t this manucript has never been partly or wholely published in or submitted to any other journals;wholely published in or submitted to any other journals;(4)The statement that all authors in the manuscript have agreed to(4)The statement that all authors in the manuscript have agreed to submit it to
5、this journal and its better to have each ones signature;submit it to this journal and its better to have each ones signature;3 3(5)The statement that the research in the manuscript has been conducted under the(5)The statement that the research in the manuscript has been conducted under the guidance
6、of international ethical standards if the research uses animals as guidance of international ethical standards if the research uses animals as experimental materials;experimental materials;(6)The statement that your manuscript satisfies the requirements of the journal.(6)The statement that your manu
7、script satisfies the requirements of the journal.(6)Suggested reviewers you think that are appropriate for this manuscript;(6)Suggested reviewers you think that are appropriate for this manuscript;(7)The statement on the inappropriate reviewers for this manuscript,and its better to(7)The statement o
8、n the inappropriate reviewers for this manuscript,and its better to state the reasons in concise words;state the reasons in concise words;(8)Some journals require the authors to briefly introduce his research purposes,(8)Some journals require the authors to briefly introduce his research purposes,me
9、thods and results.methods and results.Conciseandclear,lessthanonepage.4 4Dr.Shengli RenDr.Shengli RenDepartment of Physics,Qinghua UniversityDepartment of Physics,Qinghua University83 Shuangqing Road,Haidian District83 Shuangqing Road,Haidian DistrictBeijing 100083,P R ChinaBeijing 100083,P R ChinaE
10、mail:Email:Tel:Tel:Fax:Fax:July 18,2015July 18,2015Dear Editor:Dear Editor:This is a manuscript entitled This is a manuscript entitled“International visibility of Chinese scientific journalsInternational visibility of Chinese scientific journals”by by Shengli Ren and Ronald Rousseau.It is submitted
11、to be considered for publication as an Shengli Ren and Ronald Rousseau.It is submitted to be considered for publication as an“Article”in your journal.“Article”in your journal.All authors have read and approved this version of the article,and due care has been taken to All authors have read and appro
12、ved this version of the article,and due care has been taken to ensure the integrity of the work.Neither the entire paper nor any part of its content has been ensure the integrity of the work.Neither the entire paper nor any part of its content has been published or has been accepted elsewhere.It is
13、not being submitted to any other journal.published or has been accepted elsewhere.It is not being submitted to any other journal.5 5We believe the paper may be of particular interest to the readers of your journal as it.We believe the paper may be of particular interest to the readers of your journa
14、l as it.Correspondence should be addressed to Shengli Ren at the following address,phone and fax Correspondence should be addressed to Shengli Ren at the following address,phone and fax number,and email address:number,and email address:Thank you very much for your attention to our paper.Thank you ve
15、ry much for your attention to our paper.Sincerely yours,Sincerely yours,Shengli Ren(Shengli Ren(签名签名)Ronald Rousseau(Ronald Rousseau(签名签名)6 6大家应该也有点累了,稍作休息大家应该也有点累了,稍作休息大家有疑问的,可以询问和交流大家有疑问的,可以询问和交流大家有疑问的,可以询问和交流大家有疑问的,可以询问和交流7 7Dear Editor,Dear Editor,We would like to submit the enclosed manuscript
16、entitled GDNF Acutely Modulates Neuronal Excitability and We would like to submit the enclosed manuscript entitled GDNF Acutely Modulates Neuronal Excitability and A-type Potassium Channels in Midbrain Dopaminergic Neurons,which we wish to be considered for publication in A-type Potassium Channels i
17、n Midbrain Dopaminergic Neurons,which we wish to be considered for publication in Nature Neuroscience.Nature Neuroscience.GDNF has long been thought to be a potent neurotrophic factor for the survival of midbrain dopaminergic neurons,GDNF has long been thought to be a potent neurotrophic factor for
18、the survival of midbrain dopaminergic neurons,which are degenerated in Parkinsons disease.which are degenerated in Parkinsons disease.In this paper,we report In this paper,we report an unexpected,acute effect of GDNF on an unexpected,acute effect of GDNF on A-type potassium channels,leading to a pot
19、entiation of neuronal excitability,in the dopaminergic neurons in culture A-type potassium channels,leading to a potentiation of neuronal excitability,in the dopaminergic neurons in culture as well as in adult brain slices.as well as in adult brain slices.Further,we show that Further,we show that GD
20、NF regulates the K+channels through a mechanism that GDNF regulates the K+channels through a mechanism that involves activation of MAP kinase.involves activation of MAP kinase.Thus,this study has revealed,for the first time,Thus,this study has revealed,for the first time,an acute modulation of ion a
21、n acute modulation of ion channels by GDNF.Our findings challenge the classic view of GDNF as a long-term survival factor for midbrain channels by GDNF.Our findings challenge the classic view of GDNF as a long-term survival factor for midbrain dopaminergic neurons,and suggest that the normal functio
22、n of GDNF is to regulate neuronal excitability,and dopaminergic neurons,and suggest that the normal function of GDNF is to regulate neuronal excitability,and consequently dopamine release.These results may also have implications in the treatment of Parkinsons disease.consequently dopamine release.Th
23、ese results may also have implications in the treatment of Parkinsons disease.Due to a direct competition and conflict of interest,we request that Drs.XXX of Harvard Univ.,and YY of Yale Due to a direct competition and conflict of interest,we request that Drs.XXX of Harvard Univ.,and YY of Yale Univ
24、.not be considered as reviewers.With thanks for your consideration,I amUniv.not be considered as reviewers.With thanks for your consideration,I amSincerely yours,Sincerely yours,8 83.Things You Should Never Mention 3.Things You Should Never Mention 1.1.I Ir rr re el le ev va an nt t p pe er rs so on
25、 na al l i in nf fo or rm ma at ti io on n.2.2.A An nn no ou un nc ce em me en nt ts s o of f y yo ou ur r u un np pr ro of fe es ss si io on na al l s st ta at tu us s.3.3.H Hy yp pe e(夸夸张张).4.4.A Ap po ol lo og gi ie es s a ab bo ou ut t y yo ou ur r a ar rt ti ic cl le e (o or r y yo ou ur rs se
26、el lf f).5.5.A A d de es sc cr ri ip pt ti io on n o of f t th he e a ar rt ti ic cl le e s s f fl la aw ws s.6.6.E Ex xp pl la an na at ti io on ns s o of f w wh hy y y yo ou u a ar re e s se en nd di in ng g m ma at te er ri ia al l t th ha at t d do oe es sn n t t m ma at tc ch h t th he e p pu u
27、b bl li ic ca at ti io on n s s g gu ui id de el li in ne es s.9 97.7.D De em ma an nd ds s o or r e ex xp pe ec ct ta at ti io on ns s.8.8.O Op pi in ni io on ns s o of f y yo ou ur r f fa am mi il ly y,f fr ri ie en nd ds s,o or r w wr ri it ti in ng g t te ea ac ch he er rs s.9.9.A A l li is st t
28、 o of f p pr ri io or r r re ej je ec ct ti io on ns s.10.10.D Do on nt t f fo or rg ge et t t to o c ch he ec ck k g gr ra am mm ma ar r a an nd d s sp pe el ll li in ng g.10 10ExamplesExamplesI am currently a substitute teacher with a lifelong penchant for daydreaming with my thoughts and emotions
29、.“JACS returned this manuscript.I was advised to submit it to PCCP.Enjoy!“This whole article is,of course,just a thought.Please publish the enclosed character study.11 11Main sectionMain sectionCover letterCover letterFollow-up CorrespondenceFollow-up Correspondence(催稿信)(催稿信)Revised Manuscript Revis
30、ed Manuscript(稿件退修稿件退修)12 12Follow-up CorrespondenceFollow-up Correspondence(催稿信)If you do not receive acknowledgment within 2 weeks,call If you do not receive acknowledgment within 2 weeks,call or write to the editorial office to verify that your manuscript or write to the editorial office to verif
31、y that your manuscript was indeed received.was indeed received.13 13Dear editor,Dear editor,After the submission of our manuscript entitled Cancer classification by expression profiles:After the submission of our manuscript entitled Cancer classification by expression profiles:microRNA versus mRNA(t
32、racking number:2007-10-11332)to Nature,six weeks have microRNA versus mRNA(tracking number:2007-10-11332)to Nature,six weeks have passed.So I would like to inquire the status of our manuscript.passed.So I would like to inquire the status of our manuscript.We think that our comments on the original p
33、aper of Nature will cause widespread interest to We think that our comments on the original paper of Nature will cause widespread interest to both experts and non-experts.both experts and non-experts.This is because microRNA is a hot spot in life science;the This is because microRNA is a hot spot in
34、 life science;the author of the original paper is a VIP in cancer research based on gene expression profiles,with author of the original paper is a VIP in cancer research based on gene expression profiles,with a SCI H index of 45,total citations more than 15,000 times,and this paper citied 365 a SCI
35、 H index of 45,total citations more than 15,000 times,and this paper citied 365 times;and the algorithm we proposed outperforms the recent state-of-the-art algorithm.times;and the algorithm we proposed outperforms the recent state-of-the-art algorithm.Moreover,by using other state-of-the-art algorit
36、hms,we can also prove that the original Moreover,by using other state-of-the-art algorithms,we can also prove that the original authors main conclusions are wrong.authors main conclusions are wrong.I am looking forward to your reply.Thanks a lot.I am looking forward to your reply.Thanks a lot.14 14M
37、ain sectionMain sectionCover letterCover letterFollow-up CorrespondenceFollow-up Correspondence(催稿信)(催稿信)Revised Manuscript Revised Manuscript(稿件退修稿件退修)15 15Revised Manuscript Revised Manuscript(稿件退修稿件退修)If you receive a If you receive a decision letterdecision letter that calls for revision,that ca
38、lls for revision,examine it and the accompanying reviewers comments examine it and the accompanying reviewers comments carefully.carefully.If the reviewers are right,you should follow their directions If the reviewers are right,you should follow their directions and rewrite the manuscript accordingl
39、y.and rewrite the manuscript accordingly.If the reviewers and the editor seriously misread or If the reviewers and the editor seriously misread or misunderstood your manuscript,you may explain it misunderstood your manuscript,you may explain it reasonably and logically.reasonably and logically.16 16
40、lIncludeapointbypointresponsetothereviewerscommentsandhighlightthechangesyouhavemade.lTrytomakeyourargumentconvictivebycitingimportantreferences.17 17Responsetothereviewerscommentsonmanuscript#TA-ART-04-2015-002817We are grateful to the referees for examining our paper.Aftercarefullyconsideringthere
41、fereescommentswehaverevisedthepaper.Thefollowingdetailsourresponsetotherefereescomments.Referee1Recommendation:Idonotunderstandtheideasbehindthecalculations.Fig1aindicatesaprotonwhichmustcomefromtheelectrolyte,andalsoanelectron,whichmustcomefromtheexternalcircuit.Response:WefindthattheoriginalFig.1(
42、a)failstodepicttheVolmerreactionprocessproperly.Electronsactuallymigratewithinthematerial,ratherthanfromtheelectrolytetothematerialsurface.WethereforerevisethefiguresoastoexplicitlyshowtheprocessofelectrontransportationtoasurfaceSsitefollowedbyaprotonadsorption.18 18InFig.1bandthediscussiononp.2elec
43、tronandprotontransferaretreatedasseparatesteps.Infact,theyoccursimultaneouslyorconcerted.ThereforeatleastsurfaceIIinFig.1bmakesnosense.Also,Ihavenoideawhatismeantbythecoordinateinthisplot.Response:Wedontthinkelectronandprotontransferoccursimultaneously.Infact,protonsaremorelikelytoadsorbonanionsorne
44、gativelychargedsystems,because they have larger proton affinities and can release more heat uponadsorption.Incontrast,protonadsorptiononneutralsystemsismoredifficultdue to their smaller proton affinities(see Jolly,William L.“Modern InorganicChemistry”,for the proton affinities of both neutral and ch
45、arged molecule).Inaddition,reactive dynamic studies also show that the adsorption barrier ofprotonsishigherforneutralsystems,indicatingthatelectrontransfershouldbeprior to proton adsorption(J.Am.Chem.Soc.,2015,137(20),66926698).Nevertheless,weaddasentence“Therefore,theoverallVolmerreactioncanbesepar
46、ated into a prior electron addition process and a subsequent protonadsorption process,which is energetically more favorable than the oppositeorder.37”inthefirstparagraphofSec.IItomakethediscussionmoreconvictive.The abscissa label coordinate in Fig.1(b)refers to the ionic nuclearconfiguration,i.e.the
47、 geometries of the catalyst.The potential energy curvesschematically depict the energy change of a material with varying nuclearcoordinate.Similarpotentialsurfaceplotscanbefoundinmanyotherliteratures(e.g.BiochimicaetBiophysicaActa811(1985)265-322).Forthepurposeofmoreunderstandable,asentence“Theabsci
48、ssalabelcoordinatereferstotheionicnuclearconfiguration.”hasbeenaddedinthecaptionofFig.1(b).19 192020Onethingthatcomestomindissupportinteractions.Theauthorscalculateforfreestandingmonolayer,butanyrealHERcatalystwouldhavetobesupported.Recently,DFTcalculations(e.g.,NanoLett.2014,14,13811387)haveshownth
49、atsupportinteractionscanhaveaprofoundeffectonthehydrogenadsorptionfreeenergy.Hence,foranycorrelationwithexperimentalresultssupportinteractionswouldlikelybeimportanttoinclude.Couldtheauthorscommentonthat?Aretheconclusionslikelytochangeifsupportinteractions,includingstrain,areincluded?Response:We incl
50、ude a paragraph of discussion on the influence of supportinteractionsattheendofSec.IIIsincewefeelthatitisindeedanimportantissuetobeconsidered.Wesuggestthatsupportinteractionsmayaffectthebasal-planecatalyticactivitybecauseofthepossibleelectrontransferbetweenasupportandthecatalystonit.Foradonor-typesu
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