支气管动脉栓塞术.pptx

Click to edit Master title style,Click to edit Master text styles,Second level,Third level,Fourth level,Fifth level,2/12/2017,#,支气管动脉栓塞术,contents,Bronchial circulation,Bronchial Artery Embolization(BAE),Indications,Procedure,Complications,Two Circulations in the Lung,Bronchial Circulation,Arises from the aorta.,Part of systemic circulation.,Receives about 2%of left ventricular output.,Pulmonary Circulation,Arises from Right Ventricle.,Receives 100%of blood flow.,ANATOMICAL CONSIDERATION-Bronchial Artery,Variable anatomy in terms of origin,branching pattern,and course.,Bronchial arteries usually arise as a pair or as a common trunk,from the,descending thoracic aorta below the origin of left subclavian artery.,The standard or orthotopic origin is from the aorta between the levels of,T5 and T6(80%).,ANOMALOUS,Outside,the levels of T5 and T6.,ANOMALOUS-,Aortic arch,Internal mammary artery,Thyrocervical trunk,Subclavian,Costocervical trunk,Pericardicophrenic artery,Inferior phrenic artery.,BRONCHIAL CIRCULATION,Sometimes part of blood supply of anterior spinal artery come from bronchial vessels.,When bronchial artery embolization is performed,consideration must be given to the arterial supply to the spinal cord.,Most important is Anterior Spinal Artery.,Anterior spinal artery receives contributions from the anterior radiculo medullary branches of the intercostals and lumbar arteries.,ARTERY OF ADAMKIEWICZ,The largest anterior medullary branch.,Has variable origin from T5 L5 level,but most commonly from T8 L1 level.,In 5%of population Rt.IBT contributes to artery of Adamkiewicz.,The left bronchial arteries very rarely contribute the anterior spinal artery.,Topographical Facts:Normal Anatomy and Variations,Bronchial artery branching pattern,Cauldwell et al-,four patterns:,Type I,Type II,Type III,Type IV,Cauldwell EW,Siekert RG,Lininger RE,Anson BJ.The bronchial arteries:an anatomic study of 105 human,cadavers.Surg Gynecol Obstet 1948;86:395,412.,Type I,Incidence:40.6%,Left:2,Right:1 intercostobronchial trunk(ICBT),Bronchial Artery-Course,Leave the aorta at an upward angle,against the direction of blood flow.,Send braches to oesophagus,mediastinum,lymph nodes and nerves.,On reaching the main bronchi divide into visceral pleural branches to the mediastinal pleura and true bronchial arteries to the bronchial tree.,Bronchial Artery-Course,Spiral course around bronchi,one on either side of each other but anastomosing frequently with each other,The vessels form an arterial plexus in the adventitia from which branches pierce the muscle layer to enter the submucosa,where they break up into capillary plexus.,Supplies bronchi,nerves,walls of pulmonary vessels and intra pulmonary lymph nodes.,Bronchial Artery-Course,Arteriolar branches of the visceral pleural vessels pass along interlobular septa,reaching the interstitial tissue of the lung acinus.,The true bronchial arteries reach as far down the airways as the terminal bronchiole.,Much of the bronchial arterial blood,having gone through the submucosal capillaries,passes into the venous plexus in the adventitia.,Veins from this plexus then join pulmonary venous system.,Bronchial Artery Embolization,Minimally invasive alternative to surgery.,selective bronchial artery catheterization and angiography,followed by embolization of any identified abnormal vessels to stop the bleeding.,Considered to be the most effective nonsurgical treatment in the management of massive and recurrent hemoptysis.,Bronchial Artery Embolization,First by Remy et al.in 1973.*,Temporary or definitive,Immediate control:57100%of patients*,Embolization:bronchial and nonbronchial,Long-term control:70%-88%,Remy J,Voisin C,Dupuis C,et al:Traitement des hmoptysies par embolisation de la circulation systmique.Ann Radiol(Paris),1974;17:516.,*Remy J,Arnaud A,Fardou H,et al:Treatment of hemoptysis by embolization of bronchial arteriesRadiology 1977;122:3337.,Indications,Haemoptysis-:,Failure of conservative or bronchoscopic treatment to control bleeding.,ISRN Vascular Medicine,Volume,Article ID 263259,7 pages,Indications,Managing ruptured pulmonary artery venous malformation.,To Stabilize patients before surgical resection or medical treatment.,As a definitive therapeutic approach in patients:,-Who refuse surgery,-Who are not candidates for surgery,-Where surgery is contraindicated,Bronchial artery embolization:Managing ruptured pulmonary artery venous malformation e A case report Dharitri Goswami a,*,Shantanu Das b,1,Ashok Parida c,2,Joy Sanyal c,3.Respiratory Medicine CME 4()160e163,poor lung function,bilateral pulmonary disease,co morbidities,.,WHY BAE?,1)Bronchial circulation(90%of cases),-Pulmonary circulation(5%).,-Aorta(5%)(eg,aorto bronchial fistula,ruptured aortic aneurysm).,2),Surgery,-,Mortality 18%when performed electively,rising to 40%when performed emergently.,-,conservative approach,mortality risk of at least 50%.,3),Minimally invasive,-,clinical success-85%to 100%,-recurrence of hemorrhage 10%.,BAE-TECHNIQUE,Prior to the procedure,a brief neurological exam is performed to establish a baseline.,Femoral route/Trans-Axillary route,Monitor vitals/spo2,Sedation optional,Clean groin with antiseptics.,Adequate LA,A preliminary descending thoracic aortogram(Ionic/non ionic contrast)can be performed as a roadmap to the bronchial arteries.,BAE-TECHNIQUE,Both bronchial arteries and nonbronchial systemic arteries are opacified.,The diagnostic angiographic injections are always selective into the bronchial,intercostals,subclavian,internal mammary,intercostobronchial,and inferior phrenic arteries.,Under X-Ray machine guidance(Digital cardiac imaging with digital subtraction facility),Reverse curve catheter mikaelsson,simmons 1,shepherds hook.,Low arotic arch forward looking catheters(cobra or RC)used.,Angiographic signs of haemoptysis,ISRN Vascular Medicine Volume,Article ID 263259,7 pages,BAE-TECHNIQUE,The left main stem bronchus serves as a convenient fluoroscopic landmark for the general location of the bronchial arteries,The catheter is directed lateral or anterolateral for the right bronchial and more anterior for the left.,Bronchial arteries course of main stem bronchi towards hila.,Intercostal arteries initial cephalic course,then laterally along undersurface of rib,BAE-TECHNIQUE,The embolization materials commonly used are non-absorbable particles of,polyvinyl alcohol(PVA),(Ivalon;Nycomed SA;Paris,France),355500 m in size(some larger vessels required particles as large as 2 mm),and,fibred platinum coils,of 2 and 3mm in size(MicroNester Embolization Coils;Cook,BjaeverskovDenmark).,Catheters,:,Reverse-curved catheters(Mikaelson,Simmons I,SOS Omni),Forward-looking catheters(Cobra,HIH,RC),Sizes:4,5,or 5.5 Fr are routinely used.,Mikaelson catheter,Cobra type:curved catheter,Most commonly used,Microcatheter,Superselective catherization,Less complications,Embolizing materials,:,Absorbable gelatin sponge,Gelfoam,Pledgets(1 to 2 mm),Thrombin,Glue,Recently approved,-Embospheres,-Spherical Poly vinyl alcohol(PVA)particles,Permanent occlusive agents,Polyvinyl alcohol(PVA),Trisacryl gelatin microspheres(TGM),Gelfoam,Embolizing materials,:,PVA particles(350-500 mic),Most common&Safe,Liquid embolic agents,-ischemic necrosis,Stainless steel platinum coils,-occlude more proximal vessels.,Embolization coils:Platinum Microcoils,Embolizing materials,:,Particles 200 to 250 micr.m should be used,No ischaemia and no neurologic damage,Isobutyl-2 cyanoacrolate,Absolute alcoholUsed in pulmonary artery aneurysms,to avoid tissue ischemia and neurologic damage,Embolizing materials,:,Distal embolization,:ideal,Proximal occlusion:,temporary relief,particles 200 micr.m:avoided,-Tissue infarction,Liquid embolic agents should always be avoided because these cause tissue infarction,Clues to bronchial artery as the source of bleeding:,34,Parenchymal hypervascularity,Vascular hypertrophy,aneurysm,35,The identification of extravasated dye-INFREQUENT,Bronchopulmonary shunting,Neovascularisation,Left upper lobe bronchial artery,After Embolization,Decreased vascularity&hypertrophy,Tortous and hypertrophied vessel,Before Embolization,Right,Left,Abnormal circulation,Pre-embolisation bronchial angiogram,No abnormal circulation,Post embolisation,Bronchial artery aneurysm,Hypervascular lesion with aneurysm,Pre embolisation,Post embolisation,PVA particles,No hypervascular lesion&aneurysm,Super selective Embolization of intercostal artery,Hypervascular areas and a small amount of pulmonary arterial shunting,Decreased vasularity,POST EMBOLIZATION,PRE EMBOLIZATION,Radicular arteries,INTERCOSTAL ARTERY,Micro catheter passed,beyond radicular artery,Bronchial Artery Embolization,Success rates:,64%to 100%.,Recurrent non-massive bleeding:,1646%,Recurrence of haemoptysis may be due to:,Incomplete embolization of the bronchial vessels,Recannalization of the embolized arteries.,Presence of non-bronchial systemic arteries.,Development of collateral circulation in response to continuing pulmonary inflammation.,Bronchial Artery Embolization,Technical failure:,13%,Technical failure is caused by non-bronchial artery collaterals from systemic vessels such as the phrenic,intercostal,mammary,(PLEURA)or subclavian Arteries.,Complications of BAE,Transversemyelitis,The most feared complication due to non target occlusion of branches.,When the anterior spinal artery is identified as originating from the bronchial artery,embolisation is often deferred owing to the,risk of infaction and paraparesis.,The anterior spinal artery is the blood vessel that supplies the anterior portion of the spinal cord.,It arises from branches of the vertebral arteries and is supplied by the anterior segmental medullary arteries,including the artery of Adamkiewicz,and courses along the anterior aspect of the spinal cord.,Disruption of the anterior spinal cord leads to bilateral,disruption of the corticospinal tract,causing,motor deficits,and bilateral disruption of the spinothalamic tract,causing,sensory deficits,in the form of pain/temperature sense loss,Complications of BAE,Complications of BAE,Complications of BAE,Chest pain is the most common complication.,Dysphagia due to embolization of esophageal branches may also be encountered.,Rare complications,Aortic and bronchial necrosis,Bronchoesophageal fistula,Nontarget organ embolization(eg,ischemic colitis),Pulmonary infarction.,References,1)Haponik E F,Fein A,Chin R.Managing life-threatening hemoptysis:has anything really changed?Chest.;118(5):14311435.,2)Shigemura N,Wan I Y,Yu S C,et al.Multidisciplinary management of life-threatening massive hemoptysis:a 10-year experience.Ann Thorac Surg.;87(3):849853.,3)Marshall T J,Jackson J E.Vascular intervention in the thorax:bronchial artery embolization for haemoptysis.Eur Radiol.1997;7(8):12211227.,4)Yoon W,Kim J K,Kim Y H,Chung T W,Kang H K.Bronchial and nonbronchial systemic artery embolization for life-threatening hemoptysis:a comprehensive review.Radiographics.;22(6):13951409.,5)Fernando H C,Stein M,Benfield J R,Link D P.Role of bronchial artery embolization in the management of hemoptysis.Arch Surg.1998;133(8):862866,6)Ramakantan R,Bandekar V G,Gandhi M S,Aulakh B G,Deshmukh H L.Massive hemoptysis due to pulmonary tuberculosis:control with bronchial artery embolization.Radiology.1996;200(3):691694.,References,CONCLUSION,The development of bronchial artery embolization techniques has revolutionized the approach to hemoptysis patients.,Bronchial artery embolization possesses high rates of immediate clinical success coupled with low complication rates.,When bronchial artery angiography and embolization is performed,consideration must be given to the arterial supply to the,spine.,4),Surgery should be considered only in case where embolisation is not possible due technical difficulty and in case of embolisation failure.Otherwise bronchial artery embolisation is considered as the mainstay treatment for hemoptysis.,CONCLUSION,