急性肾炎专题知识讲座培训课件.ppt

单击此处编辑母版标题样式,单击此处编辑母版文本样式,第二级,第三级,第四级,第五级,*,急性肾炎专题知识讲座,*,急性肾炎专题知识讲座,Edema,2,急性肾炎专题知识讲座,Hematuria,3,急性肾炎专题知识讲座,Hypertension,Convulsion,Anti o ,C3,proteinuria,4,急性肾炎专题知识讲座,This glomerulus is hypercellular and capillary loops are poorly defined.This is a type of proliferative glomerulonephritis,5,急性肾炎专题知识讲座,the immune deposits are distributed in the capillary loops in a granular,bumpy pattern because of the focal nature of the deposition process,6,急性肾炎专题知识讲座,Diagonosis?Why?,edema,proteinuria,Hematuria,hypertension,.,7,急性肾炎专题知识讲座,Background,Atypical onset,edema,hematuria,proteinuria,hypertension,Persistently depressed C3(past 8-10 wk),9,急性肾炎专题知识讲座,10,急性肾炎专题知识讲座,Pathophysiology and Clinical manifestation,11,急性肾炎专题知识讲座,streptococcal antigens,specific antibodies activate the complement,system,c,3,12,急性肾炎专题知识讲座,13,急性肾炎专题知识讲座,Various cytokines,other cellular immunity factors glomerular,basement membrane,blood efusion,Hematuria,Proteinuria,cast,14,急性肾炎专题知识讲座,15,急性肾炎专题知识讲座,Various cytokines proliferation of,mesangial and epithelial cells,glomerular perfusion,glomerular,filtrate(GF)-,Severe oliguria,renal failure,16,急性肾炎专题知识讲座,17,急性肾炎专题知识讲座,glomerular filtrate(GF),-H2O,Na+,sterve -blood volume,edema,hypertention,circulatory congestion,encephalopathy.,18,急性肾炎专题知识讲座,Pathology,The hypercellularity of post-streptococcal glomerulonephritis is due to increased numbers of epithelial,endothelial,and mesangial cells as well as neutrophils in and around the capillary loops.This disease may follow several weeks after infection with certain strains of group A beta hemolytic streptococci.,19,急性肾炎专题知识讲座,Post-streptococcal glomerulonephritis is immunologically mediated,and the immune deposits are distributed in the capillary loops in a granular,bumpy pattern because of the focal nature of the deposition process,.,20,急性肾炎专题知识讲座,Clinical manifestion,Sex Age,History,Gross hematuria,edema,Hypertension,21,急性肾炎专题知识讲座,1 Circulatory congestion,2 Hypertensive encephalopathy,3 Acute renal failure,22,急性肾炎专题知识讲座,