1、?H1186-90000?2000?5?H1186A?ii?!#$%&()*+,-./01?23)*4)?56789(:;?7#!A0B?C?DEF(GHIJ-KL?M4)NO?PQR?S5)*?TU?VWXYZ_ Agilent Technologies,Inc.11575 Great Oaks Way Suite 100,MS 304B Alpharetta,GA 30319 2000 aRb?cd?efb?Rg 9?iii?hijklmno.1?p?q?.2 r?stKLuvw.3 xy?z.4 hijklm|klm(.5?x?.10 hijklm(xy.11 lm?.12 hijklm
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12、 7?(?x?jklm897:#89;?|klm?!AB9C?D EFGH;IJKLM NOPjklm|klm?QRSTURV?SWXYZ#500 amu?x9|klm(?q(xv?-“?67?350Ck?jklm?d”f gh:jklm|klmC?i?#FGHjkXYZ61-5 L?9?jklmx?5(b?v?k?d?(?eT?(lm|klmu3?_?|klm?y=%OXu?00(|klm?s-?u?(0?#?(U,jklm5?0w?lm“(?lm“0?0d 2-50 l?(?67 2 ml?+?k-?kD9|klm?kn|R?lm“-fi?kjklm5?k5(yx673M?y?d+?k?9
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14、)10?1.012.2313.414.Palatinose5.5616.7891Zorbax NH2(4.6 x 250 mm)70/30:;/?12345mAU?6?Ojklm|klm?(x?Y?A0jklmY?u(?=?“_?9|klm(?(?0?H?d?wxy?(uv?Zxdyx?6?jklm?x?d|-?x?4?lm“?N?0?x?/?|(?Q(-?4?z&B?k?0 70%#30%(yx?(l?=%?0 UV-VIS?H-6?fi?(?fi?djklm(0fi?6?0?fi|-?hijklm(xyhijklm(xyhijklm(xyhijklm(xy 11?!?$?!?$?!?$?!
15、?$?11?lm#n?&o$%&pq?I(rstn?&-AFGH?uvwx?&y C18z$%&-A$FGH)|?X_n?&?OPQRSQ?TU8-V?Q?W?hijklm?XY?5d?(hijklm?(?Z?0?8m?(?lmt?(?A0?!?0?k(?e?v9?k5(|0?5N?0?(?k?$s?e?k%&?(?(“0?lm“()?D?5p?k(?lm“djklm?(?*?x?9lm“?xy0?+,?lm“+?kq-.,+?k?67d/0?89(hx?s/.(?0?1?23/?P?0J?4?&9lm“+?k-?kqkx5x6?Oxyxy?x?fi?tx9%x5fi?fifi?78lm?qF
16、?8?5?lm?lm?lm?lm?12?*?*?*?*28?totRmAU?tRto-?tR-?-?!?k?x9flfi?x9%:=?;?(?/?dlm?(?xm?dh?x9+?k?efD?lm“?k?0?d=?(t 0)?x+?k?09?(?lm“ef?lm(ef?x?9slm?q?xef?klmh60?C?DT?hijklmx?hijklmx?hijklmx?hijklmx?13?!?)+,?!?)+,?!?)+,?!?)+,29HPLC?!#?!#?!#?!#?k?Z?0“?(xy?6?!Wlm(xyA?x?F?lm“+?kD“?OB?xy(CF?k(Z?-?(+?kksD?%Y?(xy
17、?k(?B?fi?(?“-?E?d?u(F?(F?lm?st?u(?=d?(DxyGZ?W?hijklm(?hijklm(?hijklm(?hijklm(?14?!?$-.?!?$-.?!?$-.?!?$-.30?$%?$%?$%?$%?Z?C18,C8,C4_?,?/?a?-?bC-18,C-8/?c?bd-e8fc#?ghi?(?!?j?klm?no?klp./qr8Yb?st?u#?F?HvwxF%yhizi|-?czi-?c?5H)I/?u(jklmxy?z?0Yd?(?d?klm?/?z?0U?5?$-7y?(y?-kjklm?J/0“-KL“j?dMDlm?9?0?d+?ky?0?
18、y?j(xy?z0?1xy?x?(x?x?(xy4?hijklm(?0hijklm(?0hijklm(?0hijklm(?0 15?!?$/0?!?$/0?!?$/0?!?$/0 31HPLC?&?&?&?&?0?0?0?0?!?f?f?f?f?#$?%&(?)*+,?-./01234*hijklm Zx?hx?(ddx?79N(?T?(xyi?hijklm7?0?O(?=qPHt?O(?0P?hijklm(?0hijklm(?0hijklm(?0hijklm(?0 16?(HPLC)?(HPLC)9?t?x9?t?x9?t?x9?t?x0?0?0?0?18 12?3?12?3?12?3?12
19、?3?04567045670456704567 2?HPLC?.?HPLC?.?(HPLC)?19 89:;89:;89:;89:;3?OPQV?Q?TURSQ8-#$%!%8-?W?OPQ?TU?TU?sQhijklm?$?q?Z?“fi?R)?(jklm(?(?0S?T%S?T(!d?&?dUV&/&Q?xy%&Q?A0?&S?T d?W“0ht?0X67N(T%?hixy2x?u?0=0?W“0?(HPLC)?20?9?9?9?9 4?10 m?!?#$2%0.5 m?&?()*?+?&,-./?k5YE(?67(?j?9?k?Z5A0+?d 10 m?k5YE(?“?6?5YE(?-?
20、_:(?st?)+?d 0.5*2 m9a?(?,?J?bhXu?,?(HPLC)?|?|?|?|21 AB#AB#AB#AB#5?Q?WW?Q8-y-?x?(?v?(|0=%?HPLC x?7st?u?k?|?|?k5?v(|0?k5YE(|07D?-fi?5:|c?&ef?-?JA0fl?fi?k5?v(K|7Dfl?de?|a?9?|?z?9?j?sfg?9?”5$hijWZ(TkF?|?z%?9?|?z?(HPLC)?|?|?|?|22 6?Absorbency123456789Time (min)?;?210 nm?)?|?z(k i9?|?lY?i(?v|0(?f%H9?|U,?k
21、5(-?x(k?(HPLC)?j?j?j?j?23 C?DEC?DEC?DEC?DE 7?!#?$%?&()*+?,?-./01*./2?j?(?7?A?6?(?-ZLM7?k?(?(“?qs?m?n?7(st?f%H?j?7:?o?A01p|q?7?(HPLC)?j?j?j?j?24 C?DEC?DEC?DEC?DE 8?1090 PV5?1050?1100?9rthijklm?5?k?k-sV“,?k_?!W?kZ?!W_tF?k(Z_9rs?k(uf?Nw?)?k(Z9 1090 PV51050?q?-1100?q?k?_(?t?k5?(l?ev-?6?wx#?jy?z?(?kh?C?_
22、5(#j?#?F#j?(0?_?(HPLC)h?j?h?j?h?j?h?j?25?FC?GHIJK?FC?GHIJK?FC?GHIJK?FC?GHIJK 9?q?q?q?q?56789:;7?7A7?A0(q?|?/?%&?s?0(?fl?X?%?d?9Xuevh?Z?A0?/?%&?H?Yd0%&?sV“,?-j?j?a?%?(HPLC)h?j?h?j?h?j?h?j?26 10?A?B?AB?st?“,?k%&?lm“?qt“,(ktkr 180Cq“,?:(o?6GZo?Jst“,?k?lm“?st“,?kM?(l?1090?a?“,?(HPLC)h?j?h?j?h?j?h?j?27 1
23、1?!B7C?(lm“?(?Ed10Hz?(HPLC)h?j?h?j?h?j?h?j?29 13?#$?#$?#$?#$?Gold SealSapphire InsertRuby BallSpringInsert?A0?_?x_(H(?e-?k|?_(q?st?(?st?(_?-sA?(?J“,?k?Z5M?(?_?)?6?A?(l?”?(?_?)?wx?lm“(?J“,?k?(?_?y?k?(?_?)?wx?k?fl?j?5?(HPLC)h?j?h?j?h?j?h?j?30 14?%&(?%&(?%&(?%&(?AWX?YZYZ_23451?t?5(“,?A0(!dc?LM?;?devef?
24、-P(?LM?“,(?rt“,?#?w?6?e?wx?(HPLC)h?j?h?j?h?j?h?j?31 15)*(+,?)*(+,?)*(+,?)*(+,?FlowFlowBall-Valve Housings1090Sieve&()*+&(,-?.?/0+1234?5678?j?9?(#?st9?,?t?6?(?:(?6?wx?_?LM?9?(HPLC)?j?j?j?j?32 C?DELMC?DELMC?DELMC?DELM 16?!?#$?%&()*%?2?Damping UnitPressure2%P/PPump Ripple#?1p|q(H(?d)?$?&(?o?1p|q$sm?k-6
25、?j0?(jZ9?“,?5jt?-?(HPLC)?33 NODENODENODENODE 17-./0-./0-./0-./0:?:?:?:?B?B?B?B?9x?5?W?kZ?d?9?t?5?.“?0?_?q%?Nx?GZ?hxy?6xdZ?-h?j?6?7 Z?9?k4?9?b(?5sth?x#_6?4?fi?/?Z?k?#0jO?JF?6?h?h?9qQ7k(?4?hQ?x5?s/?/?6?h?Z?Z?hw?/?h?(t=?dZ(fi0?Z?Z?(HPLC)34 PQPQPQPQ 18?3456 HPLC 7?89:;*?HPLC 3*A?BC!?+,-!?+./!01?2!?#3?!?
26、45,-xyi(?j?7?(?C?(?G?ef?(?6?(?k?-Z?7?(HPLC)?z?z?z?z 35 R?R?R?R?19?D?=EAF?GHI?JKL?MN?flx?&?HPLC lm“?(?7ux-lm“5?k(?dA HPLC?(?7?LMeF?(?i?fZ?u?qs?Xu?g9x?sd?(?“?)st?7?9?“?“?_?1 N HCl 60%?j?(HPLC)?36 STR9STR9STR9STR9 20?P?XYw?P?TU?W?1234?1234?1234?1234?ababababcdcdcdcddeNfgdeNfgdeNfgdeNfg n|(?Z-?n|9st”A0?
27、A0?6?A0?st?(?_?st0+?(?T?5?T0(?eF?9?5?A0?(?(?D?-A0?(?;I?_(?9?qJ?T5(l?_fl?t?O?x?%?T?*lm“(?(?T5(?lm“9?5?T?p#?Vs?x?-?s?x?(?/?Z?9?-?TX?7?“?“A0?4?(HPLC)?37 21OPQV?Q?TURSQ8-1234?1234?1234?1234?7hij?7hij?n?)?-?(t?#?9?5?T?fllm“0?LM?(?W(?_(t?TZd?(s?x?#fllm“(?_ev9?t?p#?T h?wxx?(f9rt?5?-dwx?T?_(?Xu?8?(HPLC)?38
28、UTR9UTR9UTR9UTR9 22?1?2?3?5?st?5?(?(?_?A0?|?6xd?0-?0q/A01050?6?0d 0.1 1.5 L?A0?(?T?06fi1.5 mL?k?O_?,?T?S?T?K?O_?lm“?_t?O?k6?O?b?fl?q?-?T9J0(?b?t?_t?A?lm“?(HPLC)?39 23P?d-d-OPG?u?W?TU6-?XY5234/05234/05234/05234/0?(st.?d6?6?9?“?“?0?H0?6?“?9?“?6?“?“6?9rtz?HM5?(?A?“?4?Z?lm“9?z?5968-5658E5“?“(st?dA0 OPA?
29、7?-FMOC 9-?“1?A0 1100?H HPLC?6?Qyv:&5(1?-6?(x?(HPLC)?40 2467%&8967%&8967%&8967%&899/:;12?ABCDEFGH?IJK+?LMN?xy?lm“!-?kU,?“U,9?/P?q“?Zd?(w?=?st?U,A0?(Peltier)!W(?“6?e?(lmx?A0“-ev9”q24?ef?(?(HPLC)HPLC fi?42 HPLC YZ9YZ9YZ9YZ9 26=HPLC?UV-VIS 65%RILS10%Electro10%FLD8%MS,-?,-?,-?,-?./?./?./?./?LC/IR Y0(HPL
30、C fi?d?H6?(UV-VIS)fi?fi?(?=?e0fibZ?A0+?(?fi?|?7dTH/?A0 UV fi?6?0?m?Ertx?&?#?(?&-“&rtx?KLXueF?-?%?XuA0fl?Qmfi?7A0?Pfi?A?A?A?A?-BCDE.BCDE.BCDE.BCDE.PAHs extracted from soil;Sup.LC-PAH 150 x4.6mm;Solv.:H2O/CH3OH=10:90FluorescenceUV-signalWL 241/394WL 270/388WL 248/411WL 302/420WL 247/504PyreneChryseneB
31、enzo(e)pyrenePeryleneBenzo(k)fluorantheneBenzo(a)pyreneBenzo(ghi)peryleneIndeno(123-cd)pyrene?/fi?0?HPLCs?Fn UV-VIS fi?#?Xu?(fi?s?Fn UV-VIS fi?(?-fl?fi?9?P(?5A0 UV fi?7fi?%?6?0fl?fi?(HPLC)HPLC fi?44 28FGHIAJ?FGHIAJ?FGHIAJ?FGHIAJ?BCKLMBCKLMBCKLMBCKLMFlecainide in SerumTherapeutic concentration:1.8mg/
32、l,20ul injectedUV and fluorescence signalFL signalUV signal?LM?V?(?Q5fi?&Q?cfi?(?rs/?&Q?V?(?Q5fiF(7d?flx?&?&Q?,?(fi?_?UV fi?(?flx?&QM5?kO%?fi?_?DA0?4F?(fi?fl?fi?JA0lmxy4?7?flx?&Qx?X flx?&?XuA0fl?Y?(?E?6?0?-?F?F?(HPLC)fifififi?7?7?7?7?49 35?-?678(LOD)9:;?ABCDDE?)67FGH?+8(LOQ)9I?JK?)IL?MNO?./?=?MQLMDL
33、?e.g.,RSD 20e.g.,S/N 3?5?)fi?(?t?u(7?LODLOQ?U-?fib LOD?cd?y(2*3 LOD(6?st?*fi?T*?&?K?7?Y?X67?(?&(u?(?LOD 6?Z*100 pgfl?-?fi?7fi*9Z(?%*HPLC?(Qmfi?(LODw?A0(?E?(?6?fi*?fi?s?0?500 ng(P?LOQ?b?cd?y(10*20UVfi?6?0?YZh?500 pg(?fi?,?6?0?U-?U?U?6:6?(fi?=?M?(Y?-Y?(?D?U7:?(fi?=?(?Q?U?09?tU?,?=?T*s?t?Us?10 x?1(,?(U
34、Vfi?(?UY?7?5 t?fl?-?fi?(?U?2 t?Qmfi?(?U?3 t?RIfi?(?UY?4 t?-?R?cd?(?E?)?7?n?(7?E?)LOD/LOQ?U-?(?c?(HPLC)UV-VIS fi?50 UV-VIS YZ9YZ9YZ9YZ9 36UV-VIS?-?bc!#$%I0ILog I0 =A =abcI?:?:?!?#$?:UV-VIS?%#$&()*+,UV-Vis fi?Y0(fi?s?H6?fi?6?0?=dM?-x?&?Z?C?/C?5(?5(?(Gcx5?Io?.I i?(?.A M?a M?M5oQQ(?b?c M5oQ(?=?.P?A?x?g6
35、?st?NC&(?9?(?U?x?&(?6?(?(HPLC)UV-VIS fi?51 37UVW?XYUVW?XYUVW?XYUVW?XY?!#$%$&$-NH-C=C-C=O-COOR-CHO-COOH-NO195190195205210200-210310202,255220,275max(nm)22-()*UV-Visfi?(fi?210 nm*850 nmA0?|?-?(?Xu(7?kJ?180 nm(?/?(?fi?z0(H?Nx?67?M5?-?H?Nx?x?5(?-?k?H?=%?-?(?&s?fi?0(M5rt?7?(?D?UH9?P(?5?(HPLC)UV-VIS fi?52
36、 38UV-VIS?-Z?Z?Z?Z?OPQRSTUVQRSTWXY,Z_QRabUV 55556767676789:89:89:89:;?=?=?=?=?ABCABCABCABCDEFG6HDEFG6HDEFG6HDEFG6HIJIJIJIJCCCC2CCCC 16W?fi?9?(6W?fi?(?(?l?P?-P?*|l?(?|l?(?U(?5F(?x?5(?QM5?(M?fi?Ni?(?9?7dT?(?.-i?(?.T*(?fi?6?6?stlmx?5(ht?d)fi?st?&(?mXuux?k(?ufi?(&Qef9?5?t?U?(HPLC)UV-VIS fi?53 39?UV-VIS?
37、PQRST UV-VIS 67FUVWX7+Y=$Z./190-900 nm$ZM 1 nm?_a$?bc$Zde&()*+,+-./#$?!0%123?+45+67UV8Vis8 7dTHfi?7?|?g?fi?/fi?7d?x?8?m?m?-:(=?P?1100 7dTH(G?(?-?7:190*850 nm(?st?!W(?!?xZ|?(?ht?7dTst?(?f(?Dh 12#$?st?(?m:=?8?9?t?5H?1024 t7dTht7dTfi?st?(?f(?t?(U?fi?.(WT*)M5?m?6?d?1*16 nm?%&T*Yh(?6?8?m?T*(7dTHfi?(-8?H?
38、m(7AT6?Z?m?6?0?5r/?&(?stlmU?(?m6?(HPLC)UV-VIS fi?55 39?_a?bc.?_a?bc.?_a?bc.?_a?bc.nrstuvwDojnojxykz|ojD?Dn?x?*9?(?55?8?)m?(?6?+,?lm?9lm?(?5?m?lm(ht?mj-?T*(?m?9?m?-?m?(rs?J?lm(m?5?&?lm9?(?mk?67?(G?Q67?:?HM5=%?-95?.?(?x0?5(H(?J?/67?(HPLC)UV-VIS fi?56 40de.fde.fde.fde.f?GC?6?5.*stBM?(?BM?)stM?-?(?/?/?_
39、6?+,x?*?rs4(Y?fi?g|t#9?“Zs?0s?0(4?fl?(?GZ)?(?d=?fi(67eF)fi*?(fiy(Y?(S/N?1x?10(?x?E?fl?(?fl?ATx?6?M5s?U(?M5?*?t?2?l?(x?3ls?fl?x?7?M5(7?M5?(?h?M5?9?W?(?Ifl?.?qF?+?T*)?m?(HPLC)fl?fi?fl?fi?fl?fi?fl?fi?58 42hihihihi-ijijijijUV?DAD-Tfi?d)%fib-?x?*LM)vux?&(fl?Q6?(?-?fi*Y?(fib-?s?D?T*(fl?m67?4(?w?A0(?-(9?(4
40、?-fl?mk?(UV?m5?(?mKA?TY?T*?m?ht?&?t?LMu9A0fl?x?g9 HPLC(u?q?V(s?ht?&jXux5?s?ht?&T*s?-?m$?t?56?J?x?7?H?(?I80?/4?(HPLC)fl?fi?fl?fi?fl?fi?fl?fi?59 43g?g?g?g?fl?4Q?G?Q?G?QP?s9:;?9?HU?(Y?.:?(?$?9fi?(?x?C?(A0A6?fi*1t?:;?zM6?fi*?(?st!?d|l?:(?l?x?Xu(?*?:Y?d)?fi?s?F(?#*9?“Z?0(4?Hst!?d|l?qt|l?j96?U?Y?(?“T?fi?Z
41、.fl?(Y?$?;?Bh?;?(.(rsst?7dT(?fi?(.?fi?=?(?$?Y?h?280 nmstCx?m?5?;1xZ?t?(?*?|l?(?+?(Cx?m-s?(E?(20 nm)UV)?(-?stE?6D(?m-?(?bX(SE?(HPLC)fl?fi?fl?fi?fl?fi?fl?fi?60?-|l?7?9=?-?m?9=?*st.?(t?tt?Xu(?2st9?(fi?$?b?(?j?9st?-?T*?/?)YZ(fib?m?0?T*?=?g?m=!;?(?#?g|l?(?(0?(Ffi?z?A(?2 PC h?s?0(Ffi?zs?J?G*fist-?(t?:?st;
42、?;?v&?2#$?(?H(?14#$?|l?I?m?(?9?(?UVfi?(HPLC)fl?fi?fl?fi?fl?fi?fl?fi?61 46?90?!?#!?$%&?()*+,-./0/0/0/0?12&?345 O2 6.7?8?#?9:?;FLD!?=?6ABABABABCD?D?D?D?EF?GH?!?!?!?!?fl?fi(?0U?tx?&6?“0?fl?fi?1?x?g5(0?7?“?(?st(“?qb?7777?-NH2 o-Phthaladehyde?7?-NHR 9-Fluorenylmethychloroformate 9-?-COOH p-Bromophenylacy
43、l bromidep-?J?,2-Naphtacyl bromide2-KJ?-OH Phenylisocyanate(?sL)-CHO,=C=O 2,4-Dinitrophenylhydrazine(2,4-7M?N)-CO-COOH 2,4-Dinitrophenylhydrazine(2,4-7M?N)?(HPLC)?fi?fi?fi?fi 62 6YZ6YZ6YZ6YZ 47?,-?./?0?123456?37&89:;NH(x)SH-?AB23456 C3DEFA B+e-(23)?fi?9K?5(?K?5x?5x?T*?K?9?d?d(?P?zG?&?K?#?(?BO?d-?Q(?
44、j(PrA?7.4?(K?P-/7(C?6?EK?-d?(?(?H?(?H?PD?x?&(?(?(HPLC)?fi?fi?fi?fi 63 46klm?klm?klm?klm?Zcde;fg?hei:jklei=min#cde;feihg?:jklei=oi?E2E1/2E1#”V?b?9fi?5A0td?d?9?d?d-?d?Zd b?d?k-?d(Pr?d?jE(W?dQ?R*d?5?d(?Iev?(Pr fi?(,?$?(g?-?&(=?:?0Jl?(?z6?fi?Sfl?x?&:(kJZ(?XT?fi?7fi?t_?/(&Q9x?V?(?/Tb?Zds?%?=dh)fi(?d)w?Y%
45、(?dP?hst?&jXuUfi?,?-b?P?(C?b(?-?(CV)?9PZ?E1?=db?(7?(?mK?7P“?*E1/2?vsh9d?P(x?Y?,?Xust?Th?E2(P?sP?(?ddb?(limiting current)?(s?h?(“?VDU,fi?(HPLC)?fi?fi?fi?fi 64 47klm?klm?klm?klm?*#?2?*#?2?*#?2?*#?2?*#?4?*#?4?*#?4?*#?44444“?*#?o?*#?o?*#?o?*#?o?*#?f?*#?f?*#?f?*#?ffifoflffifoflffifoflffifoflf?SW5?O?X)?(?
46、Y?6?d/?u?s?(thin-layer design)Z?(wall-jet design)-?+?(porous flow-through design)?+?-?q/?4(rs?/?eF?fi?5d?P(?:Ed 100%opqr!#nopqr!#nopqr!#nopqr!#stn?stn?stn?stn?;uv*wx;uv*wx;uv*wx;uv*wx?*Y?z”?EdC?0D0?Nx?DY?(stRAT?tfi?6?0?Nx?fghi5jkl?(x?-”5(Nfi 9fi?5Sfl?5?A0?d(x?A0?o#?x?(?6?h?XT6?4?&5hs/?&(m?Fw?Y%Pn?t%
47、?6?A0bn?“?ZHPLC?9st“?(PUq$P5xP-“?s?H(?9%?5?9?eF9qs?x?evk(?o?(HPLC)?fi?fi?fi?fi 66 49LC-MSt?u?GC/MS?/Z8 V?(?Zd LC x?5(stCLp?&?6?0A07dTH?z(UV M5fi?F?J?mrs?/4?.sfl?Bfi?z6?UV fi?h(.s?fi?(?&?t?z?7?qclG(A0Qmfi?6?r?t?(x?&/s?GC/MS?x?O?st?t(?z?9 LC/MS 9%uv?ww?(st?_?GC(x?0?t(?(?&?D?&?(_?h(d?0?_-#0?Ey?&?S?T%S?
48、T?|?y?-h?x?Jy?y?S?T?xy?1?xy?1?y?i?(?06?5(?|0-?x?xy?2?y?9y?*fi?d?h?5&Q(?03d?&?d?(y?s?v?5&Q?x?3d?*9?d?y?(7?x6(?0?(HPLC)?fi?fi?fi?fi 69?d?Q?h?stQ(y?h7“fi?(HED)?y?g?=?s?y?g?Qm?k?(?9?(st?S?5?(HPLC)?fi?fi?fi?fi 70 523504004505005506006507002000400060008000m/z-Abundance439467502684.653504004505005506006507
49、002000400060008000m/z-Abundance411439467495684.65Fragmentor=175 voltsFragmentor=75 voltsloss of C14 fatty acidloss of C12 fatty acidpqrsn?NMOPn?NMOPn?NMOPn?NMOP JA0?|?y?zx?x?P?qQm5?u?Q?(x?y?5?e?(phenylbutazone)(?cQ?308 k?Qm?Y?(?x?y?M+H+Qd 309?(:(?x?y?Sfl(?%P?uw?k?-?-y?q?(y?M+Na+=M+23+M+K+=M+39+M+NH4
50、+=M+18+M+X+%?Xd?#j?y?2M+H+h?q?70 M+H+S+?&?(HPLC)?fi?fi?fi?fi 71 My?q?M H-$M+X-%?Xd?#j?y?M H+S-?&?(e8?k-?j(U,Y?(?st4?X?f?t=?_?yt?(hx?&(:?(?(?y?st?Q9 q?5(?1-O1 mfj6?Q?bx?(QLM9?d?Qm?(Q?U?API?s/k-(y?z?:st?x?y?k?yv?y?5|0 x?k?DD?v(?x?-?x?j?60(?x?(?x?(?=!89?Cy?H?6?h?.CID 6?y?S?T-xy?1(y?7?F!W?Wst9!W(5?d?v?(