四川省声学学会07学术交流论文摘要.doc

网站：四川省声学学会07学术交流论文摘要一、医学超声及超声影像学1阴囊及其内容物病变的高频超声诊断 李永忠 庄华 文晓蓉 邱逦 卢强 （作者单位：四川大学华西医院超声科 ，EMAIL：lyz917邮编：610041，）摘 要 目的 探讨高频超声对阴囊及其内容物病变的诊断价值。方法 回顾性分析我院经临床治疗或手术切除、病理证实469例患者阴囊及其内容物病变的声像图表现。结果 本组469例阴囊及其内容物病变的病理类型有：闭合性外伤57例，炎性病变93例，占位病变197例，其它病变122例（睾丸扭转49例、隐睾64例、睾丸萎缩9例）。本组阴囊壁及其内容物病变的声像图表现各有其特点。结论 高频超声能测量阴囊壁的厚度，清晰显示睾丸的形态大小及内部结构变化，据阴囊及其内容物病变的声像图可初步判断其病理性质，从而为临床提供可靠的影像依据。关键词 高频超声 阴囊及其内容物病变The diagnosis of the diseased scrotum and testicle and epididym with high frequency ultrasonographyYongzhong Li，Zuang Hua, Xiaorong Wen，et alAbstract Objective To study the diagnosis value of scrotum and testicle and epididymal diseases with high frequency ultrasonography. Methods Retrospectively analysed the ultrasonographic appearance of the different scrotum and testicle and epididymal diseases in 469 patients verified by clinic diagnosis or pathology in our hospital. Results Of 469 cases,57 cases were with blunt scrotum and testicle trauma ,93 cases were with the inflamed diseases of scrotum and testicle and epididymal,occupied diseases in 197cases,other diseases in 122 cases（testis torsion in 49cases, undescend testis in 64 cases, testis atrophy in 9 cases）.The ultrasonographic appearance of the different scrotum and testicle and epididymal diseases had oneself characteristic. Conclusions the shape and size and inner structure of the scrotum and testicle and epididymal could be showed by high frequency ultrasonography,and its different diseases could be diagnosed elementary by the ultrasonographic appearances.Key words scrotum and testicle and epididymal diseases， high frequency ultrasonography2瘤内注射微泡超声辐照下对空化效应的影响卓忠雄 王红卫 皋月娟 李京京 张霞第三军医大学新桥医院超声科（重庆市400037；zzx64120）摘 要 目的 探讨超声辐照瘤内注射超声造影剂微泡对超声空化效应的影响。方法 SD大鼠Walker-256获瘤珠结节24枚随机分为3组（A组 超声辐照瘤内注射微泡、B组 单纯超声辐照、C组 单纯瘤内注射微泡）。作用后1h取肿瘤组织HE染色观察病理改变和透射电镜观察细胞膜通透性变化。结果 瘤内注射微泡超声辐照组细胞膜通透性明显增加、区域性肿瘤细胞凝固性坏死。结论 瘤内注射微泡超声辐照可增强的声空化效应作用。关键词 微泡； 瘤内注射； 辐照； 空化效应Influence to Ultrasonic Cavitation with Ultrasound Wave Irradiation Intratumoral Injected Microbubbles Zhuo Zhongxiong Wang Hongwei Gao Yuejuan et al Ultrasound Department of Xinqiao Hospital; Third Military Medical University(Chongqing city China 400037)Abstract: Purpose To investigate influence to ultrasonic cavitation with ultrasound wave irradiation intratumoral injected microbubbles. Method Twenty-four Walker-256 carcinomas were randomized 3 groups. A group was intratumoral injected microbubbles and ultrasound wave irradiation. B group was only ultrasound wave irradiation. C group was only intratumoral injected microbubbles. Result The membrane permeability of the tumor cellular membrane was palpably augmentative and the tumor celles were regionality coagulation necrosis in the group-intratumoral injected microbubbles and ultrasound wave irradiation. Cnclusion The effect of ultrasonic avatition erosion was augmented with intratumoral injected microbubbles and sound wave irradiation.Keywords: Mirovesicle; Intratumoral injected; Irradiance; Cavatition erosion3超声引导经皮穿刺肿瘤组织条注射法建立VX2兔肝癌模型李京京,卓忠雄,王冬,王宏卫,张霞(第三军医大学附属新桥医院超声诊断科,重庆 400037)摘 要 目的 探寻超声引导经皮穿刺肿瘤组织条注射法与其它种植方法建立兔VX2肝癌模型的异同。方法 30只新西兰白兔，随机分为3组，每组10只。A组：超声引导经皮穿刺肿瘤组织条注射法；B组：超声引导经皮穿刺肿瘤细胞悬液注射法；C组：开腹瘤组织块包埋种植法。观察各组肿瘤的生长特点及其接种成瘤率。结果 三种不同的植瘤方法均能成功建立移植性VX2兔肝癌模型。接种成瘤率：A组为90%、B组为90%、C组为100%，组间比较，差异无统计学意义。单发率：A组为90%、B组为20%、C组为80%；生存时间：A组为43.25.6d、B组为34.53.6d、C组为41.23.5d，B组与A、C组相比，差异有显著统计学意义。结论 超声引导经皮穿刺肿瘤组织条注射法种植建立兔VX2肝癌模型优于其它种植方法；符合本课题实验研究需求。关键词 兔；VX2肝癌；介入超声Establishment of VX2 Liver Cancer Model in Rabbit by Ultrasound Guided Puncture Injecting Tumor Tissue Institia MethodLi Jing-jing,Zhuo Zhong-xiong, Wang Dong, etal(Department of Ultrasound , Xinqiao Hospital , Third Military Medical University , Chongqing 400037 , China)Abstract : Objective To explore different means of VX2 liver cancer model in rabbit with ultrasound guided puncture tumor tissue injection Method and other implanting methods. Methods Thirty New Zealand white rabbits were randomly divided into three groups, ten rabbits in each group . Group A: ultrasound guided puncture injecting tumor tissue institia method; Group B: Ultrasound guided puncture injecting VX2 tumor fragment suspension; Group C: tumor fragments were embedded via laparotomy. The growth feature of different groups and the ratio of tumor inoculation were observed. Results The VX2 carcinoma model was made success fully in rabbits with three methods, and the ratio for carcinoma was 90%、90% and 100%,respectively, there were no significant differences between the three groups. Single noeud ratio for carcinoma was 90%、20% and 80% respectively; survival time was 43.25.6d、34.53.6d and 41.23.5d respectively, the differences between group B versus group A and group B versus group C were statistically significant. Conclusion Establishment of VX2 Liver Cancer Model in Rabbit by Ultrasound guided puncture injecting tumor tissue institia Method surpass other implanting methods,and it meets the needs of the experiment.Key words: Rabbit; VX2 carcinoma; Interventional Ultrasound 4真两性畸形的超声诊断价值李永忠1，庄华1 ，温晓玲2，黄鲁刚3(四川大学华西医院超声科 邮编 610041 Email: lyz917) 【摘 要】 目的 探讨超声诊断真两性畸形的临床价值，以提高对真两性畸形的超声诊断水平。方法 回顾性分析15例真两性畸形的临床及超声资料。结果 真两性畸形为15例中，其超声诊断提示真两性畸形12例（符合率80.0%）。结论 超声可探查患者是否存在性腺、子宫、前列腺及生殖管道等组织器官，并了解其位置、形态结构等情况，为患者的性别选择提供客观的影像学依据，因此超声对真两性畸形的诊断有着重要的价值。【关键词】真两性畸形 超声诊断 中图分类号 R445.1；R711.1The Clinic Value of The Ultrasonographic Diagnosis in True Hermaphroditismngzhong Li，Zuang Hua et al(Department of Ultrasound , Xinqiao Hospital , Third Military Medical University , Chongqing 400037 , China)Abstract Objective:To studied the clinical value of ultrasonic diagnosis in tue hermaphroditism, meanwhile to sublimate the clinical knowledge of tue hermaphroditism and ultrasonic diagnosis level . Methods: To analysed retrospectively the clinical and the ultrasonographic data of 15 tue hermaphroditism cases . Results: Of 15 truehermaphroditism cases，12 cases of true hermaphroditism （80.0%）were diagnosed by ultrasonography. Conclusion: The position and morphosis of the gonad and uterus and prostate and so on could be detected by ultrasonography.So it would be important clinical value that the true hermaphroditism would be diagnosed by ultrasonography.key words true hermaphroditism ，ultrasonicdiagnosis5卡铂缓释微球体外释药机制研究卓忠雄 皋月娟 王红卫 李京京 张霞 丁俊（第三军医大学新桥医院超声 重庆市400037；zzx64120）摘 要： 目的 探索卡铂PLGA缓释微球（微球）体外释药特性。 方法 O/O型乳化溶剂挥发法制备微球；微球在磷酸盐缓冲溶液中释放，不同时相取样计算卡铂释放量并以卡铂最初投药量百分率表达；扫描电镜观察微球超微结构变化。 结果 微球初始形态呈球形圆光滑整，释放较稳定，曲线平稳；缓冲液中微球随降解时间延长微球表面皱缩及孔洞随之增加，微球中卡铂主要通过空隙溶解与扩散。结论 微球药物释放早期以扩散为主，后期以降解及扩散联合作用。关键词： 卡铂；微球；释药；机理Study of Carboplatin-loaded PLGA Microspheres in Vitro Drug Releasing MechanismZhuo Zhongxiong Gao Yuejuan Wang Hongwei et al（Ultrasound Department of Xinqiao Hospital; Third Military Medical University(Chongqing ity China 400037)ABSTRACT Purpose To explore characteristics of carboplatin-loaded PLGA microspheres vitro drug. releasing Method The microspheres were prepared with oil in oil. The microspheres released carboplatin in phosphate buffer solution. The released carboplatin dosages were computed on different phases with initial dosage percentage express. The ultramicrostructure changes of the microspheres were observed with the scanning electron microscope. Result The incipient shape of the microsphere was circular and slick. The drug. releasing speed was stable and the drug. releasing curve was gently. The crimples and the loophole of the microspheres surface increased gradually by degradation time extend in phosphate buffer solution. The carboplatines in the microspheres were dissolved and were diffused through the loopholes. Conclusion The microsphere drug. releasing was principal by diffusion at initial stage . It was unification by diffusion and degradation at later stage.Keywo rds :Carboplatin; Microspheres; Drug. releasing; Mechanism6超声引导下胎儿脐静脉和心脏穿刺术在产前诊断中的应用罗 红 周 容 刘之英（四川大学华西第二医院超声科 610041 E-mail:luohongcd1969）摘 要 目的 探讨超声引导下胎儿脐静脉和心脏穿刺术在产前诊断中的价值。方法 对78例因各种原因行产前诊断的孕妇进行超声引导下脐静脉穿刺术和胎儿心脏穿刺术。结果 脐静脉穿刺成功率94.03%，胎儿心脏穿刺成功率100%。经胎盘穿刺36例，胎盘渗血占27.8%（10/36），经脐带穿刺67例，脐带渗血占26.9%（18/67），渗血均在30秒内自动停止。脐静脉穿刺过程中出现胎儿心动过缓者占5.97%（4/67）。脐静脉穿刺术后未出现宫内感染、晚期流产、早产、胎死宫内等并发症。结论 超声引导下胎儿脐静脉是产前诊断中一项安全、有效的方法。关键词 超声引导；胎儿脐静脉穿刺术；胎儿心脏穿刺术；产前诊断Application of ultrasonic guided cordocentesis and fetal cardiocentesis in prenatal diagnosisLuo Hong，Zhou Rong，Liu Zi-ying.(Department of Ultrasound, West China Second University Hospital of Sichuan University,Chengdu 610041，China.)Abstract Objective To explore the value of ultrasonic guided cordocentesis and fetal cardiocentesis in prenatal diagnosis. Methods Umbilical cords or fatal hearts were punctured under ultrasonic guided in 78 pregnancy women for prenatal diagnosis. Results Success rate of cordocentesis was 94.03%. success rate of fetus cardiocentesis was 100%. There were 36 cases of cordocentesis via placenta, 27.8% of which had placenta errhysis(10/36), and there were 67 cases of cordocentesis, 26.9% of which had cord errhysis (18/67). All the errhysis stopped within 30 seconds automatically. During cordocentesis, 5.97%(4/67) produced bradycardia. There was no intrauterine infection, terminal abortion, preterm delivery, or intrauterine fetal death after cordocentesis. Conclusion Ultrasonic guided cordocentesis is a safe and effective way for prenatal diagnosis.Key words Ultrasonic guided; cordocentesis; cardiocentesis ;prenatal diagnosis7二维灰阶斑点跟踪功能成像在心脏电生理中的应用罗安果 尹立雪（四川省人民医院超声医学中心 成都 610072） 摘 要：二维灰阶斑点跟踪成像（Speckle Tracking Imaging,STI）是一种观测组织运动的超声新技术，其将追踪组织声像图中的斑点信号以色彩、曲线方式选择性地成像。本文就目前该技术在心脏电生理方面的应用作一综述，主要包括以下内容：识别激动起源点，观测心肌激动传导方向和顺序，观测房颤的心脏电生理状态，观测心脏运动的同步性，测量电机械偶联时间。关键词：超声，斑点跟踪，心电生理 Clinical Significance of Two-Dimensional Ultrasound Speckle Tracking Imaging in Intracardial Cardiac Electrophysiology LUO An-guo, YIN Li-xue Echocardiography Laboratory, Sichuan Provincial Hospital, Chengdu 610072Abstract Two-dimensional speckle tracking imaging is a new ultrasound techniques for tracking the speckle signal in tissue image with the advent of color and curve-mode echocardiography, which has made a breakthrough in its observing of cardiac tissue motion,we review the application of recent cardiac electrophysiology with this techniques,which included,to discern the onset of myocardial excitement , to observe the direction and sequence of myocardial conduction, to detect the chronisation of cardiac motion, to observe the cardiac electrophysiology of atrial fibrillation, to measure the delay of electro-mechanics coupling.Key words: Ultrasound;speckle tracking imaging; cardiac electrophysiology8肺静脉畸形引流的超声诊断白文娟 唐红 解俊敏（四川大学华西医院心内科 四川成都 610041）【摘 要】肺静脉畸形引流（APVC）系胚胎发育异常导致的先天畸形，是指一支或者多支肺静脉未能直接与左心房相通，而是直接或间接通过体循环回流入右房。病理分为两型：完全型和部分型。解剖分为四型：心上型，心内型，心下型，混合型。APVC的病理生理学类似心房水平左向右分流。大多数APVC患者伴有房间隔缺损或室间隔缺损，在房水平又产生右向左分流。根据血流动力学可分为：无梗阻型和梗阻型。超声心动图诊断APVC的关键在于多切面扫查。心上型注意胸骨上窝探查，心内型注意胸骨旁左室长轴切面扫查，心下型注意剑下切面的扫查，混合型检查中应注意寻找四根肺静脉开口及引流的途径，全面扫查。【关键词】先天性心脏病；超声心动描记术；肺静脉畸形引流Diagnose of Anomalous Pulmonary Venous Connection by Using EchocardiograhyBai Wenjuan,Tang Hong,Xie Junming（Department of Cardiology, West China Hospital of Sichuan University, Chengdu, 610041）Abstract: Anomalous pulmonary venous connection（APVC） is a congenital malformation, it means one or more pulmonary vein failed to connect with left atrium, but direct or indirect connect with right atrium.It can divided total and partial types in pathology; 4 types in anatomy, include supracardiac, intra-cardiac, infracardiac, mixed type. The pathophysiology of APVC is similar to atrial septal defect. Most of the suffers companied atrial septal defect or ventricular septal defect. We divided the APVC into non-obstruction and obstruction types according to its hemodynamics. The key of APVC diagnosis is multi-planes check. In the supracardiac type we should attend the suprasternal imaging planes, the intra-cardiac type attend the parasternal long axis view, the infracardiac type attend the subcostal imaging planes, the mixed type attend the 4 pulmonary vein drain path.Keywords: congenital heart disease, echocardiography, anomalous pulmonary venous connection9超声造影在心脏瓣膜置换术前筛查冠心病的初步研究解俊敏1 唐红1 张尔永2 彭勇2 王芳1 白文娟1（四川大学华西医院心内科，1.心内科 2.胸外科 四川成都，610041）摘要 目的 研究心肌超声造影（myocardial contrast echocardiography,MCE）用于心脏瓣膜病患者术前筛查合并冠心病（coronary artery disease,CAD）的可行性及准确性。方法 对16例中老年心脏瓣膜病患者行MCE检查。以冠状动脉造影(coronary angiography,CAG)作为参考标准进行分组，观察指标包括：A、和A值，建立ROC曲线并计算敏感性及特异性。 结果 A预测中老年瓣膜病合并CAD的ROC曲线，曲线下面积为0.70，以A值2.12预测其敏感性71.0,特异性60.9。将CAG结果阴性者，按照瓣膜病变累及部位分组比较，A、A值均无统计学差异，p0.05。结论 与CAG相比较，MCE定量分析有较高的敏感性及特异性，可以作为中老年瓣膜病合并CAD的术前筛查手段。关键词 超声心动图描记术 心肌超声造影 心脏瓣膜病 冠心病 Quantitative Myocardial Contrast Echocardiography for detecting coronary artery disease combined with valvular heart diseaseJunmin Xie,Hong Tang,Eryong Zhang,Yong Peng,Fang Wang,Wenjuan Bai (Department of Cardiology, West China Hospital of Sichuan University Chengdu 610041)Abstract: Objective The aim of this study is to compare the diagnostic value of myocardial contrast echocardiography (MCE) in coronary artery disease(CAD) with coronary angiography(CAG)during the screening process.Methods 16 patients presenting to hospital with years valvular heart disease were included in the study.They were all performed MCE and CAG or 99mTc MIBI SPECT.Three parameters were A, and A.The LV segments were divided into observation group and control group based on the results of CAG.Receiver operating characteristic (ROC) was drawn and the sensitivity and specificity were calculated.Result A was significant difference between the observation group and the control group.The area under the curve (AUC) of ROC was 0.70.Fo r patients with valvular heart disease,A 2.12 predicts CAD with the sensitivity of 71.0% and specificity of 60.9%.No significantly difference was found among different types of valvular heart diseases with normal results of CAG.Conclusions Comparing MCE with CAG, quantitative analysis has a good result of sensitivity and specificity .It can be used to detect CAD in patients who combined with valvular heart disease. Key Words: echocardiography, myocardial contrast echocardiography,valvular heart disease,coronary artery disease.10人工瓣膜置换术后并发症及其超声诊断延东娥 唐红1（四川大学华西医院心内科，四川 成都 610041）摘要：人工瓣膜置换术是治疗瓣膜性心脏病的有效方法。超声心动图能无创和准确评价人工瓣膜功能及术后并发症。本文主要阐述人工瓣膜置换术后常见的并发症及其超声表现，旨在说明超声心动图对检出人工瓣膜置换术后并发症的重要意义，此外还提到了人工瓣膜的结构、种类及血流动力学特点等相关内容。关键词：人工瓣膜置换术；并发症；超声心动图Echocardiography of complication after prosthetic valve replacementDonge Yan Hong Tang（Department of Cardiology, West China Hospital of Sichuan University, Chengdu, 610041）Abstract: prosthetic valve replacement is an effective way to cure valvular heart disease