糖尿病足血管病理学——福锺堂.ppt

Pathophysiology of DiabeticVasculopathyZhijie Xi,MDGuanghua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine1.Dysregulated G-protein-coupled receptors in diabetes-associated vasculopathy 2.3.Signaling pathways that may mediate eNOS glycosylation and phosphorylation in vascular endothelial cells4.RAGE ligand axis and the role in atherogenesis 5.Potential role of C-peptide in early atherogenesis6.Atherogenic dyslipidemia leading to vascular complications and involvement of oxidative stress7.Mechanisms of hyperglycemia-induced vascular damage8.Insulin resistance as trigger of atherothrombosis 9.MicroRNAs involved in diabetic vascular disease 10.Coagulation and platelet reactivity in diabetes 11.Intracellular signalling of vascular hyperglycemic memory 12.13.14.15.16.17.18.19.20.21.22.23.24.Thanks for your attention!25.